Einblicke in die Entstehung von Mikrotubuli: Cytoskelett
Microtubules are part of the cytoskeleton and promote various essential cellular functions. Microtubules are dynamic polymers composed of heterodimeric α/ß-tubulin subunits and can assemble de novo in a ‘structural templating’ mechanism assisted by ring-like complexes containing the protein γ-tubuli...
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Deutsch |
| Veröffentlicht: |
26 March 2020
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| In: |
Biospektrum
Year: 2020, Jahrgang: 26, Heft: 2, Pages: 145-147 |
| ISSN: | 1868-6249 |
| DOI: | 10.1007/s12268-020-1341-2 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s12268-020-1341-2
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| Verfasserangaben: | Stefan Pfeffer, Elmar Schiebel |
| Zusammenfassung: | Microtubules are part of the cytoskeleton and promote various essential cellular functions. Microtubules are dynamic polymers composed of heterodimeric α/ß-tubulin subunits and can assemble de novo in a ‘structural templating’ mechanism assisted by ring-like complexes containing the protein γ-tubulin. Recent cryo-electron microscopy structures of such γ-tubulin ring complexes from vertebrates propelled our understanding of their architecture, assembly and activation mechanism. |
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| Beschreibung: | Gesehen am 18.11.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 1868-6249 |
| DOI: | 10.1007/s12268-020-1341-2 |