Cover Image

Functionalization of cellular membranes with DNA nanotechnology

Due to its versatility and programmability, DNA nanotechnology has greatly expanded the experimental toolbox for biomedical research. Recent advances allow reliable and efficient functionalization of cellular plasma membranes with a variety of synthetic DNA constructs, ranging from single strands to...

Full description

Saved in:
Bibliographic Details
Main Authors: Schönit, Andreas (Author) , Cavalcanti-Adam, Elisabetta A. (Author) , Göpfrich, Kerstin (Author)
Format: Article (Journal)
Language:English
Published: 12 March 2021
In: Trends in biotechnology
Year: 2021, Volume: 39, Issue: 11, Pages: 1208-1220
ISSN:1879-3096
DOI:10.1016/j.tibtech.2021.02.002
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tibtech.2021.02.002
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0167779921000342
Get full text
Author Notes:Andreas Schoenit, Elisabetta Ada Cavalcanti-Adam, and Kerstin Göpfrich

MARC

LEADER 00000caa a2200000 c 4500
001 1778001297
003 DE-627
005 20230426075236.0
007 cr uuu---uuuuu
008 211119s2021 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.tibtech.2021.02.002  |2 doi 
035 |a (DE-627)1778001297 
035 |a (DE-599)KXP1778001297 
035 |a (OCoLC)1341424096 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 29  |2 sdnb 
100 1 |a Schönit, Andreas  |e VerfasserIn  |0 (DE-588)1246090791  |0 (DE-627)1778001866  |4 aut 
245 1 0 |a Functionalization of cellular membranes with DNA nanotechnology  |c Andreas Schoenit, Elisabetta Ada Cavalcanti-Adam, and Kerstin Göpfrich 
264 1 |c 12 March 2021 
300 |a 13 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 19.11.2021 
520 |a Due to its versatility and programmability, DNA nanotechnology has greatly expanded the experimental toolbox for biomedical research. Recent advances allow reliable and efficient functionalization of cellular plasma membranes with a variety of synthetic DNA constructs, ranging from single strands to complex 3D DNA origami. The scope for applications, which probe biophysical parameters or equip cells with novel functions, is rapidly increasing. These applications extend from programmed cellular connectivity and tissue engineering to molecular force measurements, controlled receptor-ligand interactions, membrane-anchored biosensors, and artificial transmembrane structures. Here, we give guidance on different strategies to functionalize cellular membranes with DNA nanotechnology and summarize current trends employing membrane-anchored DNA as a tool in biophysics, cell biology, and synthetic biology. 
650 4 |a cell biology 
650 4 |a cellular plasma membrane 
650 4 |a DNA nanotechnology 
650 4 |a DNA origami 
650 4 |a lipid bilayer 
650 4 |a membrane engineering 
700 1 |a Cavalcanti-Adam, Elisabetta A.  |d 1972-  |e VerfasserIn  |0 (DE-588)1059179458  |0 (DE-627)798132256  |0 (DE-576)189133511  |4 aut 
700 1 |a Göpfrich, Kerstin  |e VerfasserIn  |0 (DE-588)1185596852  |0 (DE-627)1664987150  |4 aut 
773 0 8 |i Enthalten in  |t Trends in biotechnology  |d Amsterdam [u.a.] : Elsevier Science, 1983  |g 39(2021), 11, Seite 1208-1220  |h Online-Ressource  |w (DE-627)320490866  |w (DE-600)2011002-9  |w (DE-576)116722657  |x 1879-3096  |7 nnas  |a Functionalization of cellular membranes with DNA nanotechnology 
773 1 8 |g volume:39  |g year:2021  |g number:11  |g pages:1208-1220  |g extent:13  |a Functionalization of cellular membranes with DNA nanotechnology 
856 4 0 |u https://doi.org/10.1016/j.tibtech.2021.02.002  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S0167779921000342  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20211119 
993 |a Article 
994 |a 2021 
998 |g 1185596852  |a Göpfrich, Kerstin  |m 1185596852:Göpfrich, Kerstin  |d 700000  |d 728700  |d 160000  |d 160200  |e 700000PG1185596852  |e 728700PG1185596852  |e 160000PG1185596852  |e 160200PG1185596852  |k 0/700000/  |k 1/700000/728700/  |k 0/160000/  |k 1/160000/160200/  |p 3  |y j 
998 |g 1059179458  |a Cavalcanti-Adam, Elisabetta A.  |m 1059179458:Cavalcanti-Adam, Elisabetta A.  |d 120000  |e 120000PC1059179458  |k 0/120000/  |p 2 
999 |a KXP-PPN1778001297  |e 4003634535 
BIB |a Y 
SER |a journal 
JSO |a {"physDesc":[{"extent":"13 S."}],"language":["eng"],"title":[{"title_sort":"Functionalization of cellular membranes with DNA nanotechnology","title":"Functionalization of cellular membranes with DNA nanotechnology"}],"note":["Gesehen am 19.11.2021"],"name":{"displayForm":["Andreas Schoenit, Elisabetta Ada Cavalcanti-Adam, and Kerstin Göpfrich"]},"origin":[{"dateIssuedKey":"2021","dateIssuedDisp":"12 March 2021"}],"id":{"eki":["1778001297"],"doi":["10.1016/j.tibtech.2021.02.002"]},"recId":"1778001297","person":[{"given":"Andreas","role":"aut","display":"Schönit, Andreas","family":"Schönit"},{"given":"Elisabetta A.","family":"Cavalcanti-Adam","display":"Cavalcanti-Adam, Elisabetta A.","role":"aut"},{"given":"Kerstin","role":"aut","family":"Göpfrich","display":"Göpfrich, Kerstin"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"relHost":[{"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"320490866","part":{"issue":"11","extent":"13","year":"2021","text":"39(2021), 11, Seite 1208-1220","volume":"39","pages":"1208-1220"},"disp":"Functionalization of cellular membranes with DNA nanotechnologyTrends in biotechnology","pubHistory":["1.1983 -"],"origin":[{"dateIssuedDisp":"1983-","dateIssuedKey":"1983","publisherPlace":"Amsterdam [u.a.]","publisher":"Elsevier Science"}],"id":{"issn":["1879-3096"],"zdb":["2011002-9"],"eki":["320490866"]},"note":["Gesehen am 28.05.20"],"language":["eng"],"title":[{"title":"Trends in biotechnology","title_sort":"Trends in biotechnology"}],"physDesc":[{"extent":"Online-Ressource"}]}]} 
SRT |a SCHOENITANFUNCTIONAL1220 

Similar Items