Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients
Objective: Delirium in the elderly results in increased morbidity, mortality and functional decline. Delirium is underdiagnosed, particularly in dementia. To increase diagnostic accuracy, we investigated whether maintenance of activation assessed by EEG discriminates delirium in association with dem...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
January 17, 2008
|
| In: |
Journal of neurology, neurosurgery, and psychiatry
Year: 2008, Jahrgang: 79, Heft: 2, Pages: 119-125 |
| ISSN: | 1468-330X |
| DOI: | 10.1136/jnnp.2006.111732 |
| Online-Zugang: | Verlag, Volltext: https://doi.org/10.1136/jnnp.2006.111732 Verlag: https://jnnp.bmj.com/content/79/2/119 
|
| Verfasserangaben: | C. Thomas, U. Hestermann, S. Walther, U. Pfueller, M. Hack, P. Oster, C. Mundt, M. Weisbrod |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1778385990 | ||
| 003 | DE-627 | ||
| 005 | 20230427084519.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 211123s2008 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1136/jnnp.2006.111732 |2 doi | |
| 035 | |a (DE-627)1778385990 | ||
| 035 | |a (DE-599)KXP1778385990 | ||
| 035 | |a (OCoLC)1341430923 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Thomas, Christine |d 1961- |e VerfasserIn |0 (DE-588)1140801945 |0 (DE-627)898693845 |0 (DE-576)421101296 |4 aut | |
| 245 | 1 | 0 | |a Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients |c C. Thomas, U. Hestermann, S. Walther, U. Pfueller, M. Hack, P. Oster, C. Mundt, M. Weisbrod |
| 264 | 1 | |c January 17, 2008 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 23.11.2021 | ||
| 520 | |a Objective: Delirium in the elderly results in increased morbidity, mortality and functional decline. Delirium is underdiagnosed, particularly in dementia. To increase diagnostic accuracy, we investigated whether maintenance of activation assessed by EEG discriminates delirium in association with dementia (D+D) from dementia without delirium (DP) and cognitively unimpaired elderly subjects (CU). - Method: Routine and quantitative EEG (rEEG/qEEG) with additional prolonged activation (3 min eyes open period) were evaluated in hospitalised elderly patients with acute geriatric disease. Patients were assigned post hoc to three comparable groups (D+D/DP/CU) by expert consensus based on DSM-IV criteria. Dementia diagnosis was confirmed using cognitive and functional tests and caregiver rating (IQCODE, Informed Questionnaire of Cognitive Decline in the Elderly). - Results: While rEEG at rest showed low accuracy for a diagnosis of delirium, qEEG in DP and CU revealed a specific activation pattern of high significance found to be absent in the D+D group. Stepwise logistic regression confirmed that differentiation of D+D from DP was best resolved using activated upper alpha and delta power density which, compared with rEEG, enabled an 11% increase in diagnostic correctness to 83%, resulting in 67% sensitivity and 91% specificity. Among frail CU and D+D subjects, almost 90% were correctly classified. - Conclusion: Dementia associated with delirium can be discriminated reliably from dementia alone in a meaningful clinical setting. Thus EEG evaluation in chronic encephalopathy should be optimised by a simple activation task and spectral analysis, particularly in the elderly with dementia. | ||
| 700 | 1 | |a Hestermann, Ute Marion |d 1971- |e VerfasserIn |0 (DE-588)123818028 |0 (DE-627)085459399 |0 (DE-576)293892334 |4 aut | |
| 700 | 1 | |a Walther, Stephan |e VerfasserIn |0 (DE-588)1054946795 |0 (DE-627)792434951 |0 (DE-576)411027344 |4 aut | |
| 700 | 1 | |a Pfüller, Ute |e VerfasserIn |0 (DE-588)1078877092 |0 (DE-627)839758901 |0 (DE-576)452006066 |4 aut | |
| 700 | 1 | |a Hack, Markus |d 1971- |e VerfasserIn |0 (DE-588)122893255 |0 (DE-627)706081838 |0 (DE-576)293466750 |4 aut | |
| 700 | 1 | |a Oster, Peter |d 1946- |e VerfasserIn |0 (DE-588)174011555 |0 (DE-627)698909747 |0 (DE-576)134847903 |4 aut | |
| 700 | 1 | |a Mundt, Christoph |d 1944- |e VerfasserIn |0 (DE-588)123533759 |0 (DE-627)082613397 |0 (DE-576)293753822 |4 aut | |
| 700 | 1 | |a Weisbrod, Matthias |d 1960- |e VerfasserIn |0 (DE-588)1018045562 |0 (DE-627)690499647 |0 (DE-576)170710211 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of neurology, neurosurgery, and psychiatry |d London : BMJ Publishing Group, 1944 |g 79(2008), 2, Seite 119-125 |h Online-Ressource |w (DE-627)271594691 |w (DE-600)1480429-3 |w (DE-576)078707617 |x 1468-330X |7 nnas |a Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients |
| 773 | 1 | 8 | |g volume:79 |g year:2008 |g number:2 |g pages:119-125 |g extent:7 |a Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients |
| 856 | 4 | 0 | |u https://doi.org/10.1136/jnnp.2006.111732 |x Verlag |x Resolving-System |3 Volltext |
| 856 | 4 | 0 | |u https://jnnp.bmj.com/content/79/2/119 |x Verlag |
| 951 | |a AR | ||
| 992 | |a 20211123 | ||
| 994 | |a 2008 | ||
| 998 | |g 1018045562 |a Weisbrod, Matthias |m 1018045562:Weisbrod, Matthias |d 910000 |d 910600 |e 910000PW1018045562 |e 910600PW1018045562 |k 0/910000/ |k 1/910000/910600/ |p 8 |y j | ||
| 998 | |g 123533759 |a Mundt, Christoph |m 123533759:Mundt, Christoph |d 910000 |d 910600 |e 910000PM123533759 |e 910600PM123533759 |k 0/910000/ |k 1/910000/910600/ |p 7 | ||
| 998 | |g 174011555 |a Oster, Peter |m 174011555:Oster, Peter |d 50000 |e 50000PO174011555 |k 0/50000/ |p 6 | ||
| 998 | |g 1078877092 |a Pfüller, Ute |m 1078877092:Pfüller, Ute |d 910000 |d 910600 |e 910000PP1078877092 |e 910600PP1078877092 |k 0/910000/ |k 1/910000/910600/ |p 4 | ||
| 998 | |g 1054946795 |a Walther, Stephan |m 1054946795:Walther, Stephan |d 910000 |d 910600 |e 910000PW1054946795 |e 910600PW1054946795 |k 0/910000/ |k 1/910000/910600/ |p 3 | ||
| 998 | |g 123818028 |a Hestermann, Ute Marion |m 123818028:Hestermann, Ute Marion |p 2 | ||
| 999 | |a KXP-PPN1778385990 |e 4005106811 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"title":[{"title":"Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients","title_sort":"Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patients"}],"person":[{"role":"aut","roleDisplay":"VerfasserIn","given":"Christine","display":"Thomas, Christine","family":"Thomas"},{"roleDisplay":"VerfasserIn","given":"Ute Marion","role":"aut","family":"Hestermann","display":"Hestermann, Ute Marion"},{"role":"aut","roleDisplay":"VerfasserIn","given":"Stephan","family":"Walther","display":"Walther, Stephan"},{"display":"Pfüller, Ute","family":"Pfüller","role":"aut","roleDisplay":"VerfasserIn","given":"Ute"},{"role":"aut","given":"Markus","roleDisplay":"VerfasserIn","family":"Hack","display":"Hack, Markus"},{"family":"Oster","display":"Oster, Peter","roleDisplay":"VerfasserIn","given":"Peter","role":"aut"},{"family":"Mundt","display":"Mundt, Christoph","roleDisplay":"VerfasserIn","given":"Christoph","role":"aut"},{"roleDisplay":"VerfasserIn","given":"Matthias","role":"aut","family":"Weisbrod","display":"Weisbrod, Matthias"}],"physDesc":[{"extent":"7 S."}],"origin":[{"dateIssuedDisp":"January 17, 2008","dateIssuedKey":"2008"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"disp":"Prolonged activation EEG differentiates dementia with and without delirium in frail elderly patientsJournal of neurology, neurosurgery, and psychiatry","type":{"media":"Online-Ressource","bibl":"periodical"},"recId":"271594691","note":["Gesehen am 30.11.12","Beteil. Körp. früher: British Medical Association"],"id":{"issn":["1468-330X"],"eki":["271594691"],"zdb":["1480429-3"]},"pubHistory":["N.S. 7.1944,3 - 42.1979; 43.1980 -"],"titleAlt":[{"title":"JNNP online"},{"title":"Journal of neurology, neurosurgery & psychiatry"}],"title":[{"subtitle":"a peer review journal for health professionals and researchers in all areas of neurology","title":"Journal of neurology, neurosurgery, and psychiatry","title_sort":"Journal of neurology, neurosurgery, and psychiatry"}],"origin":[{"dateIssuedKey":"1944","publisherPlace":"London","publisher":"BMJ Publishing Group","dateIssuedDisp":"1944-"}],"corporate":[{"display":"British Medical Association","role":"isb","roleDisplay":"Herausgebendes Organ"}],"language":["eng"],"part":{"extent":"7","volume":"79","year":"2008","pages":"119-125","text":"79(2008), 2, Seite 119-125","issue":"2"}}],"language":["eng"],"recId":"1778385990","name":{"displayForm":["C. Thomas, U. Hestermann, S. Walther, U. Pfueller, M. Hack, P. Oster, C. Mundt, M. Weisbrod"]},"note":["Gesehen am 23.11.2021"],"id":{"eki":["1778385990"],"doi":["10.1136/jnnp.2006.111732"]}} | ||
| SRT | |a THOMASCHRIPROLONGEDA1720 | ||