Engineering cell-fluorescent ion track hybrid detectors
The lack of sensitive biocompatible particle track detectors has so far limited parallel detection of physical energy deposition and biological response. Fluorescent nuclear track detectors (FNTDs) based on Al2O3:C,Mg single crystals combined with confocal laser scanning microscopy (CLSM) provide 3D...
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| Main Authors: | , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
11 June 2013
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| In: |
Radiation oncology
Year: 2013, Volume: 8, Pages: 1-10 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/1748-717X-8-141 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-8-141 |
| Author Notes: | Martin Niklas, Steffen Greilich, Claudius Melzig, Mark S. Akselrod, Jürgen Debus, Oliver Jäkel and Amir Abdollahi |
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| 520 | |a The lack of sensitive biocompatible particle track detectors has so far limited parallel detection of physical energy deposition and biological response. Fluorescent nuclear track detectors (FNTDs) based on Al2O3:C,Mg single crystals combined with confocal laser scanning microscopy (CLSM) provide 3D information on ion tracks with a resolution limited by light diffraction. Here we report the development of next generation cell-fluorescent ion track hybrid detectors (Cell-Fit-HD). | ||
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