Engineering cell-fluorescent ion track hybrid detectors

The lack of sensitive biocompatible particle track detectors has so far limited parallel detection of physical energy deposition and biological response. Fluorescent nuclear track detectors (FNTDs) based on Al2O3:C,Mg single crystals combined with confocal laser scanning microscopy (CLSM) provide 3D...

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Autori principali: Niklas, Martin Anthony (Autore) , Greilich, Steffen (Autore) , Melzig, Claudius (Autore) , Akselrod, Mark S. (Autore) , Debus, Jürgen (Autore) , Jäkel, Oliver (Autore) , Abdollahi, Amir (Autore)
Natura: Article (Journal)
Lingua:inglese
Pubblicazione: 11 June 2013
In: Radiation oncology
Year: 2013, Volume: 8, Pages: 1-10
ISSN:1748-717X
DOI:10.1186/1748-717X-8-141
Accesso online:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-8-141
Testo
Note sull'autore:Martin Niklas, Steffen Greilich, Claudius Melzig, Mark S. Akselrod, Jürgen Debus, Oliver Jäkel and Amir Abdollahi
Descrizione
Riassunto:The lack of sensitive biocompatible particle track detectors has so far limited parallel detection of physical energy deposition and biological response. Fluorescent nuclear track detectors (FNTDs) based on Al2O3:C,Mg single crystals combined with confocal laser scanning microscopy (CLSM) provide 3D information on ion tracks with a resolution limited by light diffraction. Here we report the development of next generation cell-fluorescent ion track hybrid detectors (Cell-Fit-HD).
Descrizione del documento:Gesehen am 25.11.2021
Descrizione fisica:Online Resource
ISSN:1748-717X
DOI:10.1186/1748-717X-8-141