Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth
Mesenchymal stromal cells (MSC) in bone marrow have been shown to be radioresistant, which is related to pronounced DNA repair mechanisms. Intraoperative radiotherapy (IORT) during breast-conserving surgery for early breast cancer is an innovative technique applying low energy x‑ray to the tumor bed...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 February 2020
|
| In: |
Strahlentherapie und Onkologie
Year: 2020, Jahrgang: 196, Heft: 4, Pages: 398-404 |
| ISSN: | 1439-099X |
| DOI: | 10.1007/s00066-020-01586-z |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00066-020-01586-z
|
| Verfasserangaben: | Stefanie Uhlig, Anne Wuhrer, Sebastian Berlit, Benjamin Tuschy, Marc Sütterlin, Karen Bieback |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1779831811 | ||
| 003 | DE-627 | ||
| 005 | 20220208224729.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 211130s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1007/s00066-020-01586-z |2 doi | |
| 035 | |a (DE-627)1779831811 | ||
| 035 | |a (DE-599)KXP1779831811 | ||
| 035 | |a (OCoLC)1295680375 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Uhlig, Stefanie |d 1987- |e VerfasserIn |0 (DE-588)1163402206 |0 (DE-627)1027768164 |0 (DE-576)507962729 |4 aut | |
| 245 | 1 | 0 | |a Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth |c Stefanie Uhlig, Anne Wuhrer, Sebastian Berlit, Benjamin Tuschy, Marc Sütterlin, Karen Bieback |
| 264 | 1 | |c 6 February 2020 | |
| 300 | |a 7 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 30.11.2021 | ||
| 520 | |a Mesenchymal stromal cells (MSC) in bone marrow have been shown to be radioresistant, which is related to pronounced DNA repair mechanisms. Intraoperative radiotherapy (IORT) during breast-conserving surgery for early breast cancer is an innovative technique applying low energy x‑ray to the tumor bed immediately after removal of the tumor. IORT is considered to reduce the risk of local tumor recurrence by directly targeting cells of the tumor bed and altering the local microenvironment. Aim of this study was to investigate whether IORT affects the outgrowth potential of breast adipose tissue-derived MSC (bASC) as part of the tumor bed. | ||
| 700 | 1 | |a Wuhrer, Anne |d 1990- |e VerfasserIn |0 (DE-588)1188589067 |0 (DE-627)1667532804 |4 aut | |
| 700 | 1 | |a Berlit, Sebastian |d 1981- |e VerfasserIn |0 (DE-588)13983284X |0 (DE-627)613794141 |0 (DE-576)313463603 |4 aut | |
| 700 | 1 | |a Tuschy, Benjamin |d 1982- |e VerfasserIn |0 (DE-588)140931619 |0 (DE-627)623688581 |0 (DE-576)321329562 |4 aut | |
| 700 | 1 | |a Sütterlin, Marc |d 1967- |e VerfasserIn |0 (DE-588)102644067X |0 (DE-627)72673389X |0 (DE-576)371782651 |4 aut | |
| 700 | 1 | |a Bieback, Karen |d 1972- |e VerfasserIn |0 (DE-588)124509991 |0 (DE-627)376254653 |0 (DE-576)294206604 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Strahlentherapie und Onkologie |d Berlin : Springer Medizin, 1997 |g 196(2020), 4, Seite 398-404 |h Online-Ressource |w (DE-627)312407866 |w (DE-600)2003907-4 |w (DE-576)090884809 |x 1439-099X |7 nnas |a Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth |
| 773 | 1 | 8 | |g volume:196 |g year:2020 |g number:4 |g pages:398-404 |g extent:7 |a Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00066-020-01586-z |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20211130 | ||
| 993 | |a Article | ||
| 994 | |a 2020 | ||
| 998 | |g 124509991 |a Bieback, Karen |m 124509991:Bieback, Karen |d 60000 |d 63500 |e 60000PB124509991 |e 63500PB124509991 |k 0/60000/ |k 1/60000/63500/ |p 6 |y j | ||
| 998 | |g 102644067X |a Sütterlin, Marc |m 102644067X:Sütterlin, Marc |d 60000 |d 61300 |e 60000PS102644067X |e 61300PS102644067X |k 0/60000/ |k 1/60000/61300/ |p 5 | ||
| 998 | |g 140931619 |a Tuschy, Benjamin |m 140931619:Tuschy, Benjamin |d 60000 |d 61300 |e 60000PT140931619 |e 61300PT140931619 |k 0/60000/ |k 1/60000/61300/ |p 4 | ||
| 998 | |g 13983284X |a Berlit, Sebastian |m 13983284X:Berlit, Sebastian |d 60000 |d 61300 |e 60000PB13983284X |e 61300PB13983284X |k 0/60000/ |k 1/60000/61300/ |p 3 | ||
| 998 | |g 1188589067 |a Wuhrer, Anne |m 1188589067:Wuhrer, Anne |d 60000 |d 61300 |e 60000PW1188589067 |e 61300PW1188589067 |k 0/60000/ |k 1/60000/61300/ |p 2 | ||
| 998 | |g 1163402206 |a Uhlig, Stefanie |m 1163402206:Uhlig, Stefanie |d 60000 |d 63500 |e 60000PU1163402206 |e 63500PU1163402206 |k 0/60000/ |k 1/60000/63500/ |p 1 |x j | ||
| 999 | |a KXP-PPN1779831811 |e 4009148047 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"family":"Uhlig","role":"aut","display":"Uhlig, Stefanie","given":"Stefanie"},{"display":"Wuhrer, Anne","given":"Anne","role":"aut","family":"Wuhrer"},{"role":"aut","family":"Berlit","display":"Berlit, Sebastian","given":"Sebastian"},{"display":"Tuschy, Benjamin","given":"Benjamin","family":"Tuschy","role":"aut"},{"display":"Sütterlin, Marc","given":"Marc","role":"aut","family":"Sütterlin"},{"given":"Karen","display":"Bieback, Karen","family":"Bieback","role":"aut"}],"recId":"1779831811","note":["Gesehen am 30.11.2021"],"name":{"displayForm":["Stefanie Uhlig, Anne Wuhrer, Sebastian Berlit, Benjamin Tuschy, Marc Sütterlin, Karen Bieback"]},"language":["eng"],"relHost":[{"disp":"Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowthStrahlentherapie und Onkologie","type":{"media":"Online-Ressource","bibl":"periodical"},"pubHistory":["Nachgewiesen 173.1997 -"],"note":["Gesehen am 13.05.09"],"part":{"year":"2020","volume":"196","text":"196(2020), 4, Seite 398-404","pages":"398-404","extent":"7","issue":"4"},"language":["ger"],"origin":[{"dateIssuedDisp":"1997-","publisher":"Springer Medizin ; Urban & Vogel","publisherPlace":"Berlin ; Heidelberg ; [München]","dateIssuedKey":"1997"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1439-099X"],"eki":["312407866"],"zdb":["2003907-4"]},"title":[{"title_sort":"Strahlentherapie und Onkologie","subtitle":"journal of radiation oncology, biology, physics","title":"Strahlentherapie und Onkologie"}],"recId":"312407866"}],"origin":[{"dateIssuedKey":"2020","dateIssuedDisp":"6 February 2020"}],"title":[{"title_sort":"Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth","title":"Intraoperative radiotherapy for breast cancer treatment efficiently targets the tumor bed preventing breast adipose stromal cell outgrowth"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"7 S."}],"id":{"eki":["1779831811"],"doi":["10.1007/s00066-020-01586-z"]}} | ||
| SRT | |a UHLIGSTEFAINTRAOPERA6202 | ||