HIV-1 infection of CD4 T cells impairs antigen-specific B cell function

Prevention of polarized cytokine secretion at the immune synapse of infected helper T cells reduces B cell activation, providing a basis for impaired neutralizing antibody responses observed in HIV-1...

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Bibliographic Details
Main Authors: Kaw, Sheetal (Author) , Ananth, Swetha (Author) , Tsopoulidis, Nikolaos (Author) , Morath, Katharina (Author) , Coban, Bahar M. (Author) , Hohenberger, Ralph (Author) , Bulut, Cem (Author) , Klein, Florian (Author) , Stolp-Rastätter, Bettina (Author) , Fackler, Oliver Till (Author)
Format: Article (Journal)
Language:English
Published: 2020
In: The EMBO journal
Year: 2020, Volume: 39, Issue: 24, Pages: 1-18
ISSN:1460-2075
DOI:10.15252/embj.2020105594
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.15252/embj.2020105594
Verlag, kostenfrei, Volltext: https://www.embopress.org/doi/abs/10.15252/embj.2020105594
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Author Notes:Sheetal Kaw, Swetha Ananth, Nikolaos Tsopoulidis, Katharina Morath, Bahar M. Coban, Ralph Hohenberger, Olcay C. Bulut, Florian Klein, Bettina Stolp & Oliver T. Fackler
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Summary:Prevention of polarized cytokine secretion at the immune synapse of infected helper T cells reduces B cell activation, providing a basis for impaired neutralizing antibody responses observed in HIV-1...
Item Description:Gesehen am 06.12.2021
Physical Description:Online Resource
ISSN:1460-2075
DOI:10.15252/embj.2020105594