Landscape of protein-protein interactions in Drosophila immune deficiency signaling during bacterial challenge
The Drosophila defense against pathogens largely relies on the activation of two signaling pathways: immune deficiency (IMD) and Toll. The IMD pathway is triggered mainly by Gram-negative bacteria, whereas the Toll pathway responds predominantly to Gram-positive bacteria and fungi. The activation of...
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| Main Authors: | , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
June 25, 2013
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| In: |
Proceedings of the National Academy of Sciences of the United States of America
Year: 2013, Volume: 110, Issue: 26, Pages: 10717-10722 |
| ISSN: | 1091-6490 |
| DOI: | 10.1073/pnas.1304380110 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1073/pnas.1304380110 Verlag, lizenzpflichtig, Volltext: https://www.pnas.org/content/110/26/10717 |
| Author Notes: | Hidehiro Fukuyama, Yann Verdier, Yongsheng Guan, Chieko Makino-Okamura, Victoria Shilova, Xi Liu, Elie Maksoud, Jun Matsubayashi, Iman Haddad, Kerstin Spirohn, Kenichiro Ono, Charles Hetru, Jean Rossier, Trey Ideker, Michael Boutros, Joëlle Vinh, and Jules A. Hoffmann |