The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres

Constitutive heterochromatin is crucial for the integrity of chromosomes and genomic stability. Here, we show that the chromatin remodelling complex NoRC, known to silence a fraction of rRNA genes, also establishes a repressive heterochromatic structure at centromeres and telomeres, preserving the s...

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Main Authors: Poste̜pska-Igielska, Anna (Author) , Krunic, Damir (Author) , Schmitt, Nina (Author) , Greulich-Bode, Karin Maria (Author) , Boukamp, Petra (Author) , Grummt, Ingrid (Author)
Format: Article (Journal)
Language:English
Published: 25 June 2013
In: EMBO reports
Year: 2013, Volume: 14, Issue: 8, Pages: 704-710
ISSN:1469-3178
DOI:10.1038/embor.2013.87
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/embor.2013.87
Verlag, lizenzpflichtig, Volltext: https://www.embopress.org/doi/full/10.1038/embor.2013.87
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Author Notes:Anna Postepska-Igielska, Damir Krunic, Nina Schmitt, Karin Maria Greulich-Bode, Petra Boukamp & Ingrid Grummt
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The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres by Poste̜pska-Igielska, Anna (Author) , Krunic, Damir (Author) , Schmitt, Nina (Author) , Greulich-Bode, Karin Maria (Author) , Boukamp, Petra (Author) , Grummt, Ingrid (Author) ,


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