The chromatin remodelling complex NoRC safeguards genome stability by heterochromatin formation at telomeres and centromeres
Constitutive heterochromatin is crucial for the integrity of chromosomes and genomic stability. Here, we show that the chromatin remodelling complex NoRC, known to silence a fraction of rRNA genes, also establishes a repressive heterochromatic structure at centromeres and telomeres, preserving the s...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
25 June 2013
|
| In: |
EMBO reports
Year: 2013, Volume: 14, Issue: 8, Pages: 704-710 |
| ISSN: | 1469-3178 |
| DOI: | 10.1038/embor.2013.87 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/embor.2013.87 Verlag, lizenzpflichtig, Volltext: https://www.embopress.org/doi/full/10.1038/embor.2013.87 |
| Author Notes: | Anna Postepska-Igielska, Damir Krunic, Nina Schmitt, Karin Maria Greulich-Bode, Petra Boukamp & Ingrid Grummt |