GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis
The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrophages of atherosclerotic lesions, but its impact on advanced atherosclerosis is still unkno...
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| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
24 June 2013
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| In: |
European journal of medical research
Year: 2013, Jahrgang: 18, Heft: 1, Pages: 1-6 |
| ISSN: | 2047-783X |
| DOI: | 10.1186/2047-783X-18-19 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/2047-783X-18-19 Verlag, lizenzpflichtig, Volltext: https://eurjmedres.biomedcentral.com/articles/10.1186/2047-783X-18-19 
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| Verfasserangaben: | Michael R. Preusch, Matthias Baeuerle, Claudia Albrecht, Erwin Blessing, Marc Bischof, Hugo A. Katus and Florian Bea |
| Zusammenfassung: | The cytokine growth differentiation factor-15 (GDF-15), a member of the TGF beta superfamily, has recently been discovered to play an important role in cardiovascular diseases. It is mostly expressed in macrophages of atherosclerotic lesions, but its impact on advanced atherosclerosis is still unknown. This study was performed to evaluate the effects of GDF-15 in an established mouse model of advanced atherosclerosis. |
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| Beschreibung: | Gesehen am 08.12.2021 |
| Beschreibung: | Online Resource |
| ISSN: | 2047-783X |
| DOI: | 10.1186/2047-783X-18-19 |