Collagen hemostat significantly reduces time to hemostasis compared with cellulose: COBBANA, a single-center, randomized trial

Background - This single-center, randomized trial compares the hemostatic effectiveness of microfibrillar collagen and oxidized cellulose in arterial bypass surgery. - Methods - In patients undergoing arterial bypass surgery, 2 hemostats, microfibrillar collagen and oxidized cellulose, were randomly...

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Hauptverfasser: Qerimi, Bekim (VerfasserIn) , Baumann, Petra (VerfasserIn) , Hüsing, Johannes (VerfasserIn) , Knaebel, Hanns-Peter (VerfasserIn) , Schumacher, Hardy (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 17 January 2013
In: The American journal of surgery
Year: 2013, Jahrgang: 205, Heft: 6, Pages: 636-641
ISSN:1879-1883
DOI:10.1016/j.amjsurg.2012.05.033
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.amjsurg.2012.05.033
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002961012005818
Volltext
Verfasserangaben:Bekim Qerimi, Petra Baumann, PhD, Johannes Hüsing, PhD, Hanns-Peter Knaebel, MD, Hardy Schumacher, MD

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520 |a Background - This single-center, randomized trial compares the hemostatic effectiveness of microfibrillar collagen and oxidized cellulose in arterial bypass surgery. - Methods - In patients undergoing arterial bypass surgery, 2 hemostats, microfibrillar collagen and oxidized cellulose, were randomly used to achieve hemostasis. The primary endpoint was the time to hemostasis. The secondary endpoints were the complication rate, mortality, number of hemostats required, handling, and adhesion. - Results - Collagen achieved hemostasis significantly faster than cellulose, with considerably less hemostats. In addition, its ease of use was rated substantially better. - Conclusion - In arterial bypass surgery, microfibrillar collagen is more effective than oxidized cellulose in achieving hemostasis. 
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