Aging is associated with highly defined epigenetic changes in the human epidermis
Altered DNA methylation patterns represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Several studies have described global and complex age-related methylation changes, but their structural and functional significance has remained largely unclear.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 October 2013
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| In: |
Epigenetics & chromatin
Year: 2013, Jahrgang: 6, Heft: 1, Pages: 1-12 |
| ISSN: | 1756-8935 |
| DOI: | 10.1186/1756-8935-6-36 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1756-8935-6-36 Verlag, lizenzpflichtig, Volltext: https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/1756-8935-6-36 
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| Verfasserangaben: | Günter Raddatz, Sabine Hagemann, Dvir Aran, Jörn Söhle, Pranav P. Kulkarni, Lars Kaderali, Asaf Hellman, Marc Winnefeld and Frank Lyko |
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| 520 | |a Altered DNA methylation patterns represent an attractive mechanism for understanding the phenotypic changes associated with human aging. Several studies have described global and complex age-related methylation changes, but their structural and functional significance has remained largely unclear. | ||
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