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Efficacy of immune checkpoint inhibitors alone or in combination with chemotherapy in NSCLC harboring ERBB2 mutations

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Introduction - In contrast to other driver mutations, no targeted therapies have yet been approved in ERBB2-mutated NSCLC (HER2mu NSCLC). Nevertheless, several compounds have revealed promising early efficacy data, which need to be evaluated in the context of current standard approaches. Although da...

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Main Authors: Saalfeld, Felix (Author) , Wenzel, Carina (Author) , Christopoulos, Petros (Author) , Merkelbach-Bruse, Sabine (Author) , Reissig, Timm M. (Author) , Laßmann, Silke (Author) , Thiel, Sebastian (Author) , Stratmann, Jan A. (Author) , Marienfeld, Ralf (Author) , Berger, Johannes (Author) , Desuki, Alexander (Author) , Velthaus, Janna-Lisa (Author) , Kauffmann-Guerrero, Diego (Author) , Stenzinger, Albrecht (Author) , Michels, Sebastian (Author) , Herold, Thomas (Author) , Kramer, Michael (Author) , Herold, Sylvia (Author) , Tufman, Amanda (Author) , Loges, Sonja (Author) , Alt, Jürgen (Author) , Joosten, Maria (Author) , Schmidtke-Schrezenmeier, Gerlinde (Author) , Sebastian, Martin (Author) , Stephan-Falkenau, Susann (Author) , Waller, Cornelius F. (Author) , Wiesweg, Marcel (Author) , Wolf, Jürgen (Author) , Thomas, Michael (Author) , Aust, Daniela E. (Author) , Wermke, Martin (Author)
Format: Article (Journal)
Language:English
Published: 8 July 2021
In: Journal of thoracic oncology
Year: 2021, Volume: 16, Issue: 11, Pages: 1952-1958
ISSN:1556-1380
DOI:10.1016/j.jtho.2021.06.025
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jtho.2021.06.025
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1556086421022929
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Author Notes:Felix C. Saalfeld, Carina Wenzel, Petros Christopoulos, Sabine Merkelbach-Bruse, Timm M. Reissig, Silke Laßmann, Sebastian Thiel, Jan A. Stratmann, Ralf Marienfeld, Johannes Berger, Alexander Desuki, Janna-Lisa Velthaus, Diego Kauffmann-Guerrero, Albrecht Stenzinger, Sebastian Michels, Thomas Herold, Michael Kramer, Sylvia Herold, Amanda Tufman, Sonja Loges, Jürgen Alt, Maria Joosten, Gerlinde Schmidtke-Schrezenmeier, Martin Sebastian, Susann Stephan-Falkenau, Cornelius F. Waller, Marcel Wiesweg, Jürgen Wolf, Michael Thomas, Daniela E. Aust, Martin Wermke
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Gene und pathways: FGFR2‑translokationen und fusionsanalytik by Neumann, Olaf (Author) , Ball, Markus (Author) , Lehmann, Ulrich (Author) , Schirmacher, Peter (Author) , Stenzinger, Albrecht (Author) , Kazdal, Daniel (Author) ,


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Specific targeting of antiapoptotic Bcl-2 proteins as a radiosensitizing approach in solid tumors by Sobol, Benjamin (Author) , Azzam Nieto, Osama (Author) , Eberlein, Emily Lara (Author) , Scherr, Anna-Lena (Author) , Ismail, Lars (Author) , Keßler, Annika (Author) , Nader, Luisa (Author) , Schwab, Maximilian (Author) , Hoffmeister-Wittmann, Paula (Author) , Schmitt, Nathalie (Author) , Jäger, Dirk (Author) , Welte, Stefan Ezechiel (Author) , Seidensaal, Katharina (Author) , Christopoulos, Petros (Author) , Heilig, Christoph E. (Author) , Kriegsmann, Katharina (Author) , Fröhling, Stefan (Author) , Kriegsmann, Mark (Author) , Heß, Jochen (Author) , Köhler, Bruno Christian (Author) ,


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