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International multi-site initiative to develop an MRI-inclusive nomogram for side-specific prediction of extraprostatic extension of prostate cancer

For patients with newly diagnosed prostate cancer, it is important to detect tumor growth beyond the prostate, as this can affect a patient’s prognosis, influence management decisions, and alter treatment strategies. It is recognized that on prostate MRI, some instances of extraprostatic tumor growt...

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Hauptverfasser: Wibmer, Andreas G. (VerfasserIn) , Kattan, Michael W. (VerfasserIn) , Alessandrino, Francesco (VerfasserIn) , Baur, Alexander Daniel Jacques (VerfasserIn) , Boesen, Lars (VerfasserIn) , Franco, Felipe Boschini (VerfasserIn) , Bonekamp, David (VerfasserIn) , Campa, Riccardo (VerfasserIn) , Cash, Hannes (VerfasserIn) , Catalá, Violeta (VerfasserIn) , Crouzet, Sebastien (VerfasserIn) , Dinnoo, Sounil (VerfasserIn) , Eastham, James (VerfasserIn) , Fennessy, Fiona M. (VerfasserIn) , Ghabili, Kamyar (VerfasserIn) , Hohenfellner, Markus (VerfasserIn) , Levi, Angelique W. (VerfasserIn) , Ji, Xinge (VerfasserIn) , Løgager, Vibeke (VerfasserIn) , Margolis, Daniel J. (VerfasserIn) , Moldovan, Paul C. (VerfasserIn) , Panebianco, Valeria (VerfasserIn) , Penzkofer, Tobias (VerfasserIn) , Puech, Philippe (VerfasserIn) , Radtke, Jan Philipp (VerfasserIn) , Rouvière, Olivier (VerfasserIn) , Schlemmer, Heinz-Peter (VerfasserIn) , Sprenkle, Preston C. (VerfasserIn) , Tempany, Clare M. (VerfasserIn) , Vilanova, Joan C. (VerfasserIn) , Weinreb, Jeffrey (VerfasserIn) , Hricak, Hedvig (VerfasserIn) , Shukla-Dave, Amita (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 27 May 2021
In: Cancers
Year: 2021, Jahrgang: 13, Heft: 11, Pages: 1-14
ISSN:2072-6694
DOI:10.3390/cancers13112627
Online-Zugang:Resolving-System, kostenfrei: http://dx.doi.org/10.3390/cancers13112627
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2072-6694/13/11/2627
Volltext
Verfasserangaben:$hAndreas G. Wibmer, Michael W. Kattan, Francesco Alessandrino, Alexander D. J. Baur, Lars Boesen, Felipe Boschini Franco, David Bonekamp, Riccardo Campa, Hannes Cash, Violeta Catalá, Sebastien Crouzet, Sounil Dinnoo, James Eastham, Fiona M. Fennessy, Kamyar Ghabili, Markus Hohenfellner, Angelique W. Levi, Xinge Ji, Vibeke Løgager, Daniel J. Margolis, Paul C. Moldovan, Valeria Panebianco, Tobias Penzkofer, Philippe Puech, Jan Philipp Radtke, Olivier Rouvière, Heinz-Peter Schlemmer, Preston C. Sprenkle, Clare M. Tempany, Joan C. Vilanova, Jeffrey Weinreb, Hedvig Hricak and Amita Shukla-Dave
Beschreibung
Zusammenfassung:For patients with newly diagnosed prostate cancer, it is important to detect tumor growth beyond the prostate, as this can affect a patient’s prognosis, influence management decisions, and alter treatment strategies. It is recognized that on prostate MRI, some instances of extraprostatic tumor growth can be missed. In this study, we merged patient data from multiple hospitals in different countries and developed a type of mathematical formula called “nomogram” that combines MRI findings with other available patient data. The results of our study allow physicians to more accurately diagnose extraprostatic tumor growth by combining clinical, biopsy, and MRI-derived information according to their relative statistical importance.
Beschreibung:Gesehen am 20.07.2022
Beschreibung:Online Resource
ISSN:2072-6694
DOI:10.3390/cancers13112627

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