Hematopoietic SCT in Europe: data and trends in 2011
In all, 651 from 680 centers in 48 countries reported 35 660 hematopoietic SCT (HSCT) in 32 075 patients (13 470 allogeneic (42%), 18 605 autologous (58%)) to the 2011 survey. Main indications were: leukemias; 10 113 (32%; 94% allogeneic); lymphoid neoplasias; non-Hodgkin’s lymphoma, Hodgkin’s lymph...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 April 2013
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| In: |
Bone marrow transplantation
Year: 2013, Jahrgang: 48, Heft: 9, Pages: 1161-1167 |
| ISSN: | 1476-5365 |
| DOI: | 10.1038/bmt.2013.51 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/bmt.2013.51 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/bmt201351 
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| Verfasserangaben: | J.R. Passweg, H. Baldomero, M. Bregni, S. Cesaro, P. Dreger, R. F. Duarte, J.H.F. Falkenburg, N. Kröger, D. Farge-Bancel, H. Bobby Gaspar, J. Marsh, M. Mohty, C. Peters, A. Sureda, A. Velardi, C. Ruiz de Elvira and A. Madrigal |
MARC
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| 520 | |a In all, 651 from 680 centers in 48 countries reported 35 660 hematopoietic SCT (HSCT) in 32 075 patients (13 470 allogeneic (42%), 18 605 autologous (58%)) to the 2011 survey. Main indications were: leukemias; 10 113 (32%; 94% allogeneic); lymphoid neoplasias; non-Hodgkin’s lymphoma, Hodgkin’s lymphoma, plasma cell disorders; 18 433 (57%; 12% allogeneic); solid tumours; 1573 (5%; 5% allogeneic); and non-malignant disorders; 1830 (6%; 92% allogeneic). There were more unrelated donors than HLA identical sibling donors (54% versus 39%); proportion of peripheral blood as stem cell source was 99% for autologous and 73% for allogeneic HSCT. Cord blood was only used in allogeneic transplants (6% of total). In the past 10 years, the overall number of transplants has increased by 53%. Allogeneic HSCT have doubled (from 7272 to 14 549) while, autologous have increased by 32% and continue to increase by about 1100 HSCT per year since 2001. In the past 2 years, an increase of >2000 HSCT per year was seen. Transplant activity is shown by team size. For allogeneic HSCT, we show use of reduced-intensity conditioning versus myeloablative conditioning across Europe and use of post-transplant donor lymphocyte infusions with considerable variation across different countries. | ||
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