Buchumschlag

Hydrogel micropillars with integrin selective peptidomimetic functionalized nanopatterned tops: a new tool for the measurement of cell traction forces transmitted through αvβ3- or α5β1-integrins

Poly(ethylene glycol) micropillars with gold nanopatterns on top are functionalized with two integrin selective ligands. This platform is a powerful new tool to determine the specific contribution of traction forces involved in cell adhesion mediated by α5 β1- and αvβ3- integrins. Cells adherent via...

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Bibliographische Detailangaben
Hauptverfasser: Rahmouni, Sabri (VerfasserIn) , Lindner, Aaron (VerfasserIn) , Rechenmacher, Florian (VerfasserIn) , Neubauer, Stefanie (VerfasserIn) , Sobahi, Tariq Rashad Ali (VerfasserIn) , Kessler, Horst (VerfasserIn) , Cavalcanti-Adam, Elisabetta A. (VerfasserIn) , Spatz, Joachim P. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: August 5, 2013
In: Advanced materials
Year: 2013, Jahrgang: 25, Heft: 41, Pages: 5869-5874
ISSN:1521-4095
DOI:10.1002/adma.201301338
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/adma.201301338
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/adma.201301338
Volltext
Verfasserangaben:Sabri Rahmouni, Aaron Lindner, Florian Rechenmacher, Stefanie Neubauer, Tariq Rashad Ali Sobahi, Horst Kessler, Elisabetta Ada Cavalcanti-Adam, Joachim Pius Spatz
Beschreibung
Zusammenfassung:Poly(ethylene glycol) micropillars with gold nanopatterns on top are functionalized with two integrin selective ligands. This platform is a powerful new tool to determine the specific contribution of traction forces involved in cell adhesion mediated by α5 β1- and αvβ3- integrins. Cells adherent via α5 β1-integrins have a tendency to exert higher maximum forces than cells adhering via αvβ3-integrins.
Beschreibung:Gesehen am 05.01.2022
Beschreibung:Online Resource
ISSN:1521-4095
DOI:10.1002/adma.201301338

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