Atacicept in relapsed/refractory multiple myeloma or active Waldenström's macroglobulinemia: a phase I study
Advanced multiple myeloma (MM) and Waldenström's macroglobulinemia (WM) are incurable B-cell malignancies. This is the first full clinical report of atacicept, a fusion protein that binds to and neutralises the B-cell survival factors, B-lymphocyte stimulator (BLyS) and A proliferation-inducin...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 September 2009
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| In: |
British journal of cancer
Year: 2009, Volume: 101, Issue: 7, Pages: 1051-1058 |
| ISSN: | 1532-1827 |
| DOI: | 10.1038/sj.bjc.6605241 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/sj.bjc.6605241 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/6605241 |
| Author Notes: | J.-F. Rossi, J. Moreaux, D. Hose, G. Requirand, M. Rose, V. Rouillé, I. Nestorov, G. Mordenti, H. Goldschmidt, A. Ythier and B. Klein |
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| 520 | |a Advanced multiple myeloma (MM) and Waldenström's macroglobulinemia (WM) are incurable B-cell malignancies. This is the first full clinical report of atacicept, a fusion protein that binds to and neutralises the B-cell survival factors, B-lymphocyte stimulator (BLyS) and A proliferation-inducing ligand (APRIL), in MM and WM. | ||
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