Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Childhood posterior fossa group A ependymomas demonstrate integrated metabolic and epigenetic pathways that can be disrupted by metformin.
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
6 Oct 2021
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| In: |
Science translational medicine
Year: 2021, Volume: 13, Issue: 614, Pages: 1-13 |
| ISSN: | 1946-6242 |
| DOI: | 10.1126/scitranslmed.abc0497 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1126/scitranslmed.abc0497 Verlag, lizenzpflichtig, Volltext: https://www.science.org/doi/abs/10.1126/scitranslmed.abc0497 
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| Author Notes: | Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Siva Kumar Natarajan, Matthew Pun, Jill Bayliss, Martin P. Ogrodzinski, Drew Pratt, Brendan Mullan, Debra Hawes, Fusheng Yang, Chao Lu, Benjamin R. Sabari, Abhinav Achreja, Jin Heon, Olamide Animasahun, Marcin Cieslik, Christopher Dunham, Stephen Yip, Juliette Hukin, Joanna J. Phillips, Miriam Bornhorst, Andrea M. Griesinger, Andrew M. Donson, Nicholas K. Foreman, Hugh J. L. Garton, Jason Heth, Karin Muraszko, Javad Nazarian, Carl Koschmann, Li Jiang, Mariella G. Filbin, Deepak Nagrath, Marcel Kool, Andrey Korshunov, Stefan M. Pfister, Richard J. Gilbertson, C. David Allis, Arul M. Chinnaiyan, Sophia Y. Lunt, Stefan Blüml, Alexander R. Judkins, Sriram Venneti |
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