Sorafenib treatment is save and may affect survival of recurrent hepatocellular carcinoma after liver transplantation
Recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) is a rare but challenging condition. In most cases, the recurrent tumor is presented with extrahepatic spread. Therefore, systemic treatment with sorafenib has to be assessed. Because of a plethora of possible drug interaction...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
4 October 2013
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| In: |
Langenbeck's archives of surgery
Year: 2013, Jahrgang: 398, Heft: 8, Pages: 1123-1128 |
| ISSN: | 1435-2451 |
| DOI: | 10.1007/s00423-013-1114-1 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00423-013-1114-1
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| Verfasserangaben: | Jan Pfeiffenberger, Ronald Koschny, Katrin Hoffmann, Arianeb Mehrabi, Anne Schmitz, Boris Radeleff, Wolfgang Stremmel, Peter Schemmer, Tom M. Ganten |
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| 520 | |a Recurrent hepatocellular carcinoma (HCC) after liver transplantation (LT) is a rare but challenging condition. In most cases, the recurrent tumor is presented with extrahepatic spread. Therefore, systemic treatment with sorafenib has to be assessed. Because of a plethora of possible drug interactions, e.g., with immunosuppressant or anti-infective therapy, safety and feasibility of sorafenib treatment requires special attention. | ||
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