Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT
The application of spacer gel represents a promising approach to reliably spare the rectal frontal wall during particle therapy (IJROBP 76:1251-1258, 2010). In order to qualify the spacer gel for the clinical use in particle therapy, a variety of measurements were performed in order to ensure the bi...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 June 2013
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| In: |
Radiation oncology
Year: 2013, Jahrgang: 8, Heft: 1, Pages: 1-12 |
| ISSN: | 1748-717X |
| DOI: | 10.1186/1748-717X-8-134 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1748-717X-8-134
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| Verfasserangaben: | Antoni Ruciński, Julia Bauer, Patrick Campbell, Stephan Brons, Daniel Unholtz, Gregor Habl, Klaus Herfarth, Jürgen Debus, Christoph Bert, Katia Parodi, Oliver Jäkel and Thomas Haberer |
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| 520 | |a The application of spacer gel represents a promising approach to reliably spare the rectal frontal wall during particle therapy (IJROBP 76:1251-1258, 2010). In order to qualify the spacer gel for the clinical use in particle therapy, a variety of measurements were performed in order to ensure the biological compatibility of the gel, its physical stability during and after the irradiation, and a proper definition of the gel in terms of the Hounsfield Unit (HU) values for the treatment planning system. The potential for the use of the spacer gel for particle therapy monitoring with off-line Positron Emission Tomography (PET) was also investigated. | ||
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