Diastereoselective synthesis of 1,3-syn-oxazines via a tandem hemiaminalization and Tsuji-Trost reaction
A novel domino sequence for the rapid assembly of 1,3-syn-substituted oxazines is reported. Mechanistically, the one-pot procedure is based on a three-step sequential process involving a hemiaminalization and Tsuji-Trost reaction. The process generates up to two new stereogenic centers in a concise...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
18.02.2013
|
| In: |
Synlett
Year: 2013, Jahrgang: 24, Heft: 5, Pages: 625-629 |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0032-1318300 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1055/s-0032-1318300 Verlag, lizenzpflichtig, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0032-1318300 
|
| Verfasserangaben: | Bin Tang, Liang Wang, Dirk Menche |
| Zusammenfassung: | A novel domino sequence for the rapid assembly of 1,3-syn-substituted oxazines is reported. Mechanistically, the one-pot procedure is based on a three-step sequential process involving a hemiaminalization and Tsuji-Trost reaction. The process generates up to two new stereogenic centers in a concise and convergent fashion from simple and readily available starting materials. |
|---|---|
| Beschreibung: | Gesehen am 31.01.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1437-2096 |
| DOI: | 10.1055/s-0032-1318300 |