Wapl is an essential regulator of chromatin structure and chromosome segregation
Depletion of the cohesin-associated protein Wapl in mice is shown to increase the residence time of cohesin on DNA, which leads to clustering of cohesin in axial structures, and causes chromatin condensation in interphase chromosomes; the findings suggest that cohesin could have an architectural rol...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
25 August 2013
|
| In: |
Nature
Year: 2013, Jahrgang: 501, Heft: 7468, Pages: 564-568 |
| ISSN: | 1476-4687 |
| DOI: | 10.1038/nature12471 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/nature12471 Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/nature12471 
|
| Verfasserangaben: | Antonio Tedeschi, Gordana Wutz, Sébastien Huet, Markus Jaritz, Annelie Wuensche, Erika Schirghuber, Iain Finley Davidson, Wen Tang, David A. Cisneros, Venugopal Bhaskara, Tomoko Nishiyama, Alipasha Vaziri, Anton Wutz, Jan Ellenberg & Jan-Michael Peters |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1788426037 | ||
| 003 | DE-627 | ||
| 005 | 20220820121410.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220203s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1038/nature12471 |2 doi | |
| 035 | |a (DE-627)1788426037 | ||
| 035 | |a (DE-599)KXP1788426037 | ||
| 035 | |a (OCoLC)1341439632 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Tedeschi, Antonio |e VerfasserIn |0 (DE-588)1226265146 |0 (DE-627)1747239992 |4 aut | |
| 245 | 1 | 0 | |a Wapl is an essential regulator of chromatin structure and chromosome segregation |c Antonio Tedeschi, Gordana Wutz, Sébastien Huet, Markus Jaritz, Annelie Wuensche, Erika Schirghuber, Iain Finley Davidson, Wen Tang, David A. Cisneros, Venugopal Bhaskara, Tomoko Nishiyama, Alipasha Vaziri, Anton Wutz, Jan Ellenberg & Jan-Michael Peters |
| 264 | 1 | |c 25 August 2013 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 03.02.2022 | ||
| 520 | |a Depletion of the cohesin-associated protein Wapl in mice is shown to increase the residence time of cohesin on DNA, which leads to clustering of cohesin in axial structures, and causes chromatin condensation in interphase chromosomes; the findings suggest that cohesin could have an architectural role in interphase chromosome organization. | ||
| 650 | 4 | |a Humanities and Social Sciences | |
| 650 | 4 | |a multidisciplinary | |
| 650 | 4 | |a Science | |
| 700 | 1 | |a Wutz, Gordana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Huet, Sébastien |e VerfasserIn |4 aut | |
| 700 | 1 | |a Jaritz, Markus |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wünsche, Annelie |e VerfasserIn |0 (DE-588)1263232922 |0 (DE-627)1811328377 |4 aut | |
| 700 | 1 | |a Schirghuber, Erika |e VerfasserIn |4 aut | |
| 700 | 1 | |a Davidson, Iain Finley |e VerfasserIn |4 aut | |
| 700 | 1 | |a Tang, Wen |e VerfasserIn |4 aut | |
| 700 | 1 | |a Cisneros, David A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Bhaskara, Venugopal |e VerfasserIn |4 aut | |
| 700 | 1 | |a Nishiyama, Tomoko |e VerfasserIn |4 aut | |
| 700 | 1 | |a Vaziri, Alipasha |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wutz, Anton |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ellenberg, Jan |d 1967- |e VerfasserIn |0 (DE-588)120495902 |0 (DE-627)696725835 |0 (DE-576)292249640 |4 aut | |
| 700 | 1 | |a Peters, Jan-Michael |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Nature |d London [u.a.] : Nature Publ. Group, 1869 |g 501(2013), 7468, Seite 564-568 |h Online-Ressource |w (DE-627)240151402 |w (DE-600)1413423-8 |w (DE-576)079718426 |x 1476-4687 |7 nnas |a Wapl is an essential regulator of chromatin structure and chromosome segregation |
| 773 | 1 | 8 | |g volume:501 |g year:2013 |g number:7468 |g pages:564-568 |g extent:5 |a Wapl is an essential regulator of chromatin structure and chromosome segregation |
| 856 | 4 | 0 | |u https://doi.org/10.1038/nature12471 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.nature.com/articles/nature12471 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220203 | ||
| 993 | |a Editorial | ||
| 994 | |a 2013 | ||
| 998 | |g 120495902 |a Ellenberg, Jan |m 120495902:Ellenberg, Jan |d 140000 |e 140000PE120495902 |k 0/140000/ |p 14 | ||
| 999 | |a KXP-PPN1788426037 |e 405069879X | ||
| BIB | |a Y | ||
| SER | |a newspaper | ||
| JSO | |a {"physDesc":[{"extent":"5 S."}],"relHost":[{"title":[{"title":"Nature","subtitle":"international weekly journal of science","title_sort":"Nature"}],"part":{"volume":"501","text":"501(2013), 7468, Seite 564-568","extent":"5","year":"2013","issue":"7468","pages":"564-568"},"titleAlt":[{"title":"Nature <London>"},{"title":"Nature"}],"pubHistory":["1.1869/70 - ; auch mit durchgehender Nr.-Zählung"],"language":["eng"],"recId":"240151402","note":["Gesehen am 19.02.2019"],"disp":"Wapl is an essential regulator of chromatin structure and chromosome segregationNature","type":{"media":"Online-Ressource","bibl":"newspaper"},"id":{"issn":["1476-4687"],"zdb":["1413423-8"],"eki":["240151402"]},"origin":[{"publisherPlace":"London [u.a.] ; London","publisher":"Nature Publ. Group ; Macmillan","dateIssuedKey":"1869","dateIssuedDisp":"1869-"}],"physDesc":[{"extent":"Online-Ressource"}]}],"origin":[{"dateIssuedDisp":"25 August 2013","dateIssuedKey":"2013"}],"id":{"doi":["10.1038/nature12471"],"eki":["1788426037"]},"name":{"displayForm":["Antonio Tedeschi, Gordana Wutz, Sébastien Huet, Markus Jaritz, Annelie Wuensche, Erika Schirghuber, Iain Finley Davidson, Wen Tang, David A. Cisneros, Venugopal Bhaskara, Tomoko Nishiyama, Alipasha Vaziri, Anton Wutz, Jan Ellenberg & Jan-Michael Peters"]},"type":{"bibl":"article-newspaper","media":"Online-Ressource"},"note":["Gesehen am 03.02.2022"],"language":["eng"],"recId":"1788426037","title":[{"title_sort":"Wapl is an essential regulator of chromatin structure and chromosome segregation","title":"Wapl is an essential regulator of chromatin structure and chromosome segregation"}],"person":[{"roleDisplay":"VerfasserIn","display":"Tedeschi, Antonio","role":"aut","family":"Tedeschi","given":"Antonio"},{"roleDisplay":"VerfasserIn","display":"Wutz, Gordana","role":"aut","family":"Wutz","given":"Gordana"},{"role":"aut","display":"Huet, Sébastien","roleDisplay":"VerfasserIn","given":"Sébastien","family":"Huet"},{"role":"aut","display":"Jaritz, Markus","roleDisplay":"VerfasserIn","given":"Markus","family":"Jaritz"},{"family":"Wünsche","given":"Annelie","display":"Wünsche, Annelie","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Erika","family":"Schirghuber","role":"aut","roleDisplay":"VerfasserIn","display":"Schirghuber, Erika"},{"role":"aut","display":"Davidson, Iain Finley","roleDisplay":"VerfasserIn","given":"Iain Finley","family":"Davidson"},{"role":"aut","display":"Tang, Wen","roleDisplay":"VerfasserIn","given":"Wen","family":"Tang"},{"display":"Cisneros, David A.","roleDisplay":"VerfasserIn","role":"aut","family":"Cisneros","given":"David A."},{"role":"aut","roleDisplay":"VerfasserIn","display":"Bhaskara, Venugopal","given":"Venugopal","family":"Bhaskara"},{"family":"Nishiyama","given":"Tomoko","roleDisplay":"VerfasserIn","display":"Nishiyama, Tomoko","role":"aut"},{"family":"Vaziri","given":"Alipasha","roleDisplay":"VerfasserIn","display":"Vaziri, Alipasha","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Wutz, Anton","role":"aut","family":"Wutz","given":"Anton"},{"display":"Ellenberg, Jan","roleDisplay":"VerfasserIn","role":"aut","family":"Ellenberg","given":"Jan"},{"display":"Peters, Jan-Michael","roleDisplay":"VerfasserIn","role":"aut","family":"Peters","given":"Jan-Michael"}]} | ||
| SRT | |a TEDESCHIANWAPLISANES2520 | ||