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Taking into account nucleosomes for predicting gene expression

The eukaryotic genome is organized in a chain of nucleosomes that consist of 145-147bp of DNA wrapped around a histone octamer protein core. Binding of transcription factors (TF) to nucleosomal DNA is frequently impeded, which makes it a challenging task to calculate TF occupancy at a given regulato...

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Main Authors: Teif, Vladimir (Author) , Erdel, Fabian (Author) , Beshnova, Daria A (Author) , Vainshtein, Yevhen (Author) , Mallm, Jan-Philipp (Author) , Rippe, Karsten (Author)
Format: Article (Journal)
Language:English
Published: 21 March 2013
In: Methods
Year: 2013, Volume: 62, Issue: 1, Pages: 26-38
ISSN:1095-9130
DOI:10.1016/j.ymeth.2013.03.011
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ymeth.2013.03.011
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1046202313000807
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Author Notes:Vladimir B. Teif, Fabian Erdel, Daria A. Beshnova, Yevhen Vainshtein, Jan-Philipp Mallm, Karsten Rippe

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