Multigene assays for classification, prognosis, and prediction in breast cancer: a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen Nutzen
<p>Gene signatures which are based on multigene profiling assays have been developed for the purpose to better define the prognosis and prediction of therapy results in early-stage breast cancer. These assays were designed to be more specific than conventional clinico-pathologic parameters in...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2013
|
| In: |
Geburtshilfe und Frauenheilkunde
Year: 2013, Jahrgang: 73, Heft: 9, Pages: 932-940 |
| ISSN: | 1438-8804 |
| DOI: | 10.1055/s-0033-1350831 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1055/s-0033-1350831 Verlag, kostenfrei, Volltext: http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1350831 
|
| Verfasserangaben: | P. Sinn, S. Aulmann, R. Wirtz, S. Schott, F. Marmé, Z. Varga, A. Lebeau, H. Kreipe, A. Schneeweiss |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1788442741 | ||
| 003 | DE-627 | ||
| 005 | 20220820121644.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220203s2013 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1055/s-0033-1350831 |2 doi | |
| 035 | |a (DE-627)1788442741 | ||
| 035 | |a (DE-599)KXP1788442741 | ||
| 035 | |a (OCoLC)1341441304 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Sinn, Peter |d 1957- |e VerfasserIn |0 (DE-588)1022590944 |0 (DE-627)717004783 |0 (DE-576)365646342 |4 aut | |
| 245 | 1 | 0 | |a Multigene assays for classification, prognosis, and prediction in breast cancer |b a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen Nutzen |c P. Sinn, S. Aulmann, R. Wirtz, S. Schott, F. Marmé, Z. Varga, A. Lebeau, H. Kreipe, A. Schneeweiss |
| 246 | 3 | 1 | |a Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom |b ein kritischer Review zum Hintergrund und klinischen Nutzen |
| 264 | 1 | |c 2013 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Publikationsdatum: 11. Oktober 2013 (online) | ||
| 500 | |a Gesehen am 03.02.2022 | ||
| 520 | |a <p>Gene signatures which are based on multigene profiling assays have been developed for the purpose to better define the prognosis and prediction of therapy results in early-stage breast cancer. These assays were designed to be more specific than conventional clinico-pathologic parameters in the selection of patients for (neo-)adjuvant treatment and in effect help to avoid unnecessary cytotoxic treatment. In this review we describe molecular risk scores, for which tests are commercially available (PAM50®, MammaTyper®, MammaPrint®, Oncotype DX®, Endopredict®, Genomic Grade Index®) and IHC risk scores (Mammostrat® and IHC4), and discuss the current evidence of their clinical use.</p> | ||
| 700 | 1 | |a Aulmann, Sebastian |d 1973- |e VerfasserIn |0 (DE-588)124520197 |0 (DE-627)363393021 |0 (DE-576)294211519 |4 aut | |
| 700 | 1 | |a Wirtz, R. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schott, Sarah |d 1981- |e VerfasserIn |0 (DE-588)133730816 |0 (DE-627)552697281 |0 (DE-576)27460678X |4 aut | |
| 700 | 1 | |a Marmé, Frederik |d 1974- |e VerfasserIn |0 (DE-588)132561972 |0 (DE-627)52394893X |0 (DE-576)299226549 |4 aut | |
| 700 | 1 | |a Varga, Z. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Lebeau, A. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kreipe, H. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schneeweiss, Andreas |d 1961- |e VerfasserIn |0 (DE-588)109972554 |0 (DE-627)632849630 |0 (DE-576)327251859 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Geburtshilfe und Frauenheilkunde |d Stuttgart : Thieme, 1980 |g 73(2013), 9, Seite 932-940 |h Online-Ressource |w (DE-627)324451970 |w (DE-600)2026496-3 |w (DE-576)279447663 |x 1438-8804 |7 nnas |a Multigene assays for classification, prognosis, and prediction in breast cancer a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen Nutzen |
| 773 | 1 | 8 | |g volume:73 |g year:2013 |g number:9 |g pages:932-940 |g extent:9 |a Multigene assays for classification, prognosis, and prediction in breast cancer a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen Nutzen |
| 856 | 4 | 0 | |u https://doi.org/10.1055/s-0033-1350831 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u http://www.thieme-connect.de/DOI/DOI?10.1055/s-0033-1350831 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220203 | ||
| 993 | |a Article | ||
| 994 | |a 2013 | ||
| 998 | |g 109972554 |a Schneeweiss, Andreas |m 109972554:Schneeweiss, Andreas |d 910000 |d 910400 |d 50000 |e 910000PS109972554 |e 910400PS109972554 |e 50000PS109972554 |k 0/910000/ |k 1/910000/910400/ |k 0/50000/ |p 9 |y j | ||
| 998 | |g 132561972 |a Marmé, Frederik |m 132561972:Marmé, Frederik |d 910000 |d 910400 |e 910000PM132561972 |e 910400PM132561972 |k 0/910000/ |k 1/910000/910400/ |p 5 | ||
| 998 | |g 133730816 |a Schott, Sarah |m 133730816:Schott, Sarah |d 910000 |d 910400 |e 910000PS133730816 |e 910400PS133730816 |k 0/910000/ |k 1/910000/910400/ |p 4 | ||
| 998 | |g 124520197 |a Aulmann, Sebastian |m 124520197:Aulmann, Sebastian |d 50000 |e 50000PA124520197 |k 0/50000/ |p 2 | ||
| 998 | |g 1022590944 |a Sinn, Peter |m 1022590944:Sinn, Peter |d 910000 |d 912000 |d 50000 |e 910000PS1022590944 |e 912000PS1022590944 |e 50000PS1022590944 |k 0/910000/ |k 1/910000/912000/ |k 0/50000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1788442741 |e 405073771X | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"type":{"bibl":"article-journal","media":"Online-Ressource"},"physDesc":[{"extent":"9 S."}],"id":{"doi":["10.1055/s-0033-1350831"],"eki":["1788442741"]},"name":{"displayForm":["P. Sinn, S. Aulmann, R. Wirtz, S. Schott, F. Marmé, Z. Varga, A. Lebeau, H. Kreipe, A. Schneeweiss"]},"origin":[{"dateIssuedKey":"2013","dateIssuedDisp":"2013"}],"relHost":[{"language":["ger"],"title":[{"title_sort":"Geburtshilfe und Frauenheilkunde","title":"Geburtshilfe und Frauenheilkunde"}],"note":["Erscheint monatlich","Gesehen am 08.11.2024"],"recId":"324451970","pubHistory":["Nachgewiesen 40.1980 -"],"part":{"extent":"9","pages":"932-940","year":"2013","text":"73(2013), 9, Seite 932-940","issue":"9","volume":"73"},"titleAlt":[{"title":"GEBFRA"}],"disp":"Multigene assays for classification, prognosis, and prediction in breast cancer a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen NutzenGeburtshilfe und Frauenheilkunde","id":{"doi":["10.1055/s-00000020"],"issn":["1438-8804"],"zdb":["2026496-3"],"eki":["324451970"]},"physDesc":[{"extent":"Online-Ressource"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"1980-","publisher":"Thieme","dateIssuedKey":"1980","publisherPlace":"Stuttgart ; New York, NY"}]}],"recId":"1788442741","language":["eng"],"title":[{"subtitle":"a critical review on the background and clinical utility = Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom : ein kritischer Review zum Hintergrund und klinischen Nutzen","title_sort":"Multigene assays for classification, prognosis, and prediction in breast cancer","title":"Multigene assays for classification, prognosis, and prediction in breast cancer"}],"note":["Publikationsdatum: 11. Oktober 2013 (online)","Gesehen am 03.02.2022"],"person":[{"role":"aut","given":"Peter","display":"Sinn, Peter","family":"Sinn"},{"role":"aut","given":"Sebastian","display":"Aulmann, Sebastian","family":"Aulmann"},{"display":"Wirtz, R.","family":"Wirtz","role":"aut","given":"R."},{"display":"Schott, Sarah","family":"Schott","role":"aut","given":"Sarah"},{"display":"Marmé, Frederik","family":"Marmé","role":"aut","given":"Frederik"},{"display":"Varga, Z.","family":"Varga","role":"aut","given":"Z."},{"display":"Lebeau, A.","family":"Lebeau","role":"aut","given":"A."},{"family":"Kreipe","display":"Kreipe, H.","given":"H.","role":"aut"},{"role":"aut","given":"Andreas","display":"Schneeweiss, Andreas","family":"Schneeweiss"}],"titleTranslated":[{"translated":"Multigenassays zur Beurteilung der Klassifikation, Prognose und Prädiktion beim Mammakarzinom"}]} | ||
| SRT | |a SINNPETERAMULTIGENEA2013 | ||