Prognostic impact of lymph node involvement and the extent of lymphadenectomy (LAD) in adenocarcinoma of the esophagogastric junction (AEG)

The prognostic importance of lymph node (LN) involvement for patients with adenocarcinoma of the esophagogastric junction (AEG) is well-known. In the latest edition of the UICC staging system, the number of metastatic LNs was taken into account, while the extent of lymphadenectomy (LAD) remains unad...

Full description

Saved in:
Bibliographic Details
Main Authors: Peters, Leila (Author) , Blank, Susanne (Author) , Weichert, Wilko (Author) , Jäger, Dirk (Author) , Springfeld, Christoph (Author) , Hochreiter, Marcel (Author) , Büchler, Markus W. (Author) , Ott, Katja (Author)
Format: Article (Journal)
Language:English
Published: 2013
In: Langenbeck's archives of surgery
Year: 2013, Volume: 398, Issue: 7, Pages: 973-981
ISSN:1435-2451
DOI:10.1007/s00423-013-1101-6
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00423-013-1101-6
Verlag, lizenzpflichtig, Volltext: https://link.springer.com/article/10.1007%2Fs00423-013-1101-6
Get full text
Author Notes:Leila Sisic, Susanne Blank, Wilko Weichert, Dirk Jäger, Christoph Springfeld, Marcel Hochreiter, Markus Büchler, Katja Ott
Description
Summary:The prognostic importance of lymph node (LN) involvement for patients with adenocarcinoma of the esophagogastric junction (AEG) is well-known. In the latest edition of the UICC staging system, the number of metastatic LNs was taken into account, while the extent of lymphadenectomy (LAD) remains unaddressed. Removal of at least six LNs is recommended, but there is no defined minimum number as to classify as (y)pN0. We examined the prognostic value of the number of positive LNs, number of LNs removed, and LN ratio (LNR) in order to determine the influence of an adequate LAD on overall survival (OS).
Item Description:Published online: 26 July 2013
Gesehen am 03.02.2022
Physical Description:Online Resource
ISSN:1435-2451
DOI:10.1007/s00423-013-1101-6