Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma - CapRI: study protocol (ISRCTN62866759)

After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-year survival of 21% achieved with adjuvant chemotherapy. Investigators from the Virginia Maso...

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Main Authors: Knaebel, Hanns-Peter (Author) , Märten, Angela (Author) , Schmidt, Jan (Author) , Hoffmann, Katrin (Author) , Seiler, Christoph (Author) , Lindel, Katja (Author) , Schmitz-Winnenthal, Friedrich Hubertus (Author) , Fritz, Stefan (Author) , Herrmann, Thomas (Author) , Goldschmidt, Hartmut (Author) , Krempien, Robert (Author) , Mansmann, Ulrich (Author) , Debus, Jürgen (Author) , Diehl, Volker (Author) , Büchler, Markus W. (Author)
Format: Article (Journal)
Language:English
Published: 12 April 2005
In: BMC cancer
Year: 2005, Volume: 5, Pages: 1-8
ISSN:1471-2407
DOI:10.1186/1471-2407-5-37
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2407-5-37
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Author Notes:H.P. Knaebel, A. Märten, J. Schmidt, K. Hoffmann, C. Seiler, K. Lindel, H. Schmitz-Winnenthal, S. Fritz, T. Herrmann, H. Goldschmidt, R. Krempien, U. Mansmann, J. Debus, V. Diehl and M.W. Büchler
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Summary:After surgical intervention with curative intention in specialised centres the five-year survival of patients with carcinoma of the exocrine pancreas is only 15%. The ESPAC-1 trial showed an increased five-year survival of 21% achieved with adjuvant chemotherapy. Investigators from the Virginia Mason Clinic have reported a 5-year survival rate of 55% in a phase II trial evaluating adjuvant chemotherapy, immunotherapy and external-beam radiation
Item Description:Gesehen am 04.02.2022
Physical Description:Online Resource
ISSN:1471-2407
DOI:10.1186/1471-2407-5-37