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Global public health security and justice for vaccines and therapeutics in the COVID-19 pandemic

A Lancet Commission for COVID-19 task force is shaping recommendations to achieve vaccine and therapeutics access, justice, and equity. This includes ensuring safety and effectiveness harmonized through robust systems of global pharmacovigilance and surveillance. Global production requires expanding...

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Main Authors: Hotez, Peter J. (Author) , Batista, Carolina (Author) , Amor, Yanis Ben (Author) , Ergonul, Onder (Author) , Figueroa, J Peter (Author) , Gilbert, Sarah (Author) , Gursel, Mayda (Author) , Hassanain, Mazen (Author) , Kang, Gagandeep (Author) , Kaslow, David C. (Author) , Kim, Jerome H. (Author) , Lall, Bhavna (Author) , Larson, Heidi (Author) , Naniche, Denise (Author) , Sheahan, Timothy (Author) , Shoham, Shmuel (Author) , Wilder-Smith, Annelies (Author) , Sow, Samba O. (Author) , Strub-Wourgaft, Nathalie (Author) , Yadav, Prashant (Author) , Bottazzi, Maria Elena (Author)
Format: Article (Journal)
Language:English
Published: 3 August 2021
In: EClinicalMedicine
Year: 2021, Volume: 39, Pages: 1-10
ISSN:2589-5370
DOI:10.1016/j.eclinm.2021.101053
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.eclinm.2021.101053
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S2589537021003333
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Author Notes:Peter J. Hotez, Carolina Batista, Yanis Ben Amor, Onder Ergonul, J Peter Figueroa, Sarah Gilbert, Mayda Gursel, Mazen Hassanain, Gagandeep Kang, David C. Kaslow, Jerome H. Kim, Bhavna Lall, Heidi Larson, Denise Naniche, Timothy Sheahan, Shmuel Shoham, Annelies Wilder-Smith, Samba O. Sow, Nathalie Strub-Wourgaft, Prashant Yadav, Maria Elena Bottazzi

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520 |a A Lancet Commission for COVID-19 task force is shaping recommendations to achieve vaccine and therapeutics access, justice, and equity. This includes ensuring safety and effectiveness harmonized through robust systems of global pharmacovigilance and surveillance. Global production requires expanding support for development, manufacture, testing, and distribution of vaccines and therapeutics to low- and middle-income countries (LMICs). Global intellectual property rules must not stand in the way of research, production, technology transfer, or equitable access to essential health tools, and in context of pandemics to achieve increased manufacturing without discouraging innovation. Global governance around product quality requires channelling widely distributed vaccines through WHO prequalification (PQ)/emergency use listing (EUL) mechanisms and greater use of national regulatory authorities. A World Health Assembly (WHA) resolution would facilitate improvements and consistency in quality control and assurances. Global health systems require implementing steps to strengthen national systems for controlling COVID-19 and for influenza vaccinations for adults including pregnant and lactating women. A collaborative research network should strive to establish open access databases for bioinformatic analyses, together with programs directed at human capacity utilization and strengthening. Combating anti-science recognizes the urgency for countermeasures to address a global-wide disinformation movement dominating the internet and infiltrating parliaments and local governments. 
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