Yes-associated protein up-regulates Jagged-1 and activates the NOTCH pathway in human hepatocellular carcinoma
Background & Aims - Cancer cells often lose contact inhibition to undergo anchorage-independent proliferation and become resistant to apoptosis by inactivating the Hippo signaling pathway, resulting in activation of the transcriptional co-activator yes-associated protein (YAP). However, the onco...
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
15 February 2013
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| In: |
Gastroenterology
Year: 2013, Jahrgang: 144, Heft: 7, Pages: 1530-1542 |
| ISSN: | 1528-0012 |
| DOI: | 10.1053/j.gastro.2013.02.009 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1053/j.gastro.2013.02.009 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0016508513002205 |
| Verfasserangaben: | Darjus Felix Tschaharganeh, Xin Chen, Philipp Latzko, Mona Malz, Matthias Martin Gaida, Klaus Felix, Sara Ladu, Stephan Singer, Federico Pinna, Norbert Gretz, Carsten Sticht, Maria Lauda Tomasi, Salvatore Delogu, Matthias Evert, Biao Fan, Silvia Ribback, Lijie Jiang, Stefania Brozzetti, Frank Bergmann, Frank Dombrowski, Peter Schirmacher, Diego Francesco Calvisi, and Kai Breuhahn |