Assessment of secondary neutrons in particle therapy by Monte Carlo simulations

Objective. The purpose of this study is to estimate the energy and angular distribution of secondary neutrons inside a phantom in hadron therapy, which will support decisions on detector choice and experimental setup design for in-phantom secondary neutron measurements. Approach. Dedicated Monte Car...

Full description

Saved in:
Bibliographic Details
Main Authors: Vedelago, José (Author) , Geser, Federico A. (Author) , Muñoz, Iván Domingo (Author) , Stabilini, Alberto (Author) , Yukihara, Eduardo G. (Author) , Jäkel, Oliver (Author)
Format: Article (Journal)
Language:English
Published: 17 January 2022
In: Physics in medicine and biology
Year: 2022, Volume: 67, Issue: 1, Pages: 1-18
ISSN:1361-6560
DOI:10.1088/1361-6560/ac431b
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1088/1361-6560/ac431b
Verlag, lizenzpflichtig, Volltext: https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=DynamicDOIArticle&SrcApp=WOS&KeyAID=10.1088%2F1361-6560%2Fac431b&DestApp=DOI&SrcAppSID=C6bvvFqkejUrUKINkLa&SrcJTitle=PHYSICS+IN+MEDICINE+AND+BIOLOGY&DestDOIRegistrantName=IOP+Publishing
Get full text
Author Notes:José Vedelago, Federico A. Geser, Iván D. Munoz, Alberto Stabilini, Eduardo G. Yukihara and Oliver Jäkel

MARC

LEADER 00000caa a2200000 c 4500
001 1789597854
003 DE-627
005 20240821094557.0
007 cr uuu---uuuuu
008 220215s2022 xx |||||o 00| ||eng c
024 7 |a 10.1088/1361-6560/ac431b  |2 doi 
035 |a (DE-627)1789597854 
035 |a (DE-599)KXP1789597854 
035 |a (OCoLC)1341441725 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Vedelago, José  |e VerfasserIn  |0 (DE-588)1251835139  |0 (DE-627)1789602149  |4 aut 
245 1 0 |a Assessment of secondary neutrons in particle therapy by Monte Carlo simulations  |c José Vedelago, Federico A. Geser, Iván D. Munoz, Alberto Stabilini, Eduardo G. Yukihara and Oliver Jäkel 
264 1 |c 17 January 2022 
300 |a 18 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 15.02.2022 
520 |a Objective. The purpose of this study is to estimate the energy and angular distribution of secondary neutrons inside a phantom in hadron therapy, which will support decisions on detector choice and experimental setup design for in-phantom secondary neutron measurements. Approach. Dedicated Monte Carlo simulations were implemented, considering clinically relevant energies of protons, helium and carbon ions. Since scored quantities can vary from different radiation transport models, the codes FLUKA, TOPAS and MCNP were used. The geometry of an active scanning beam delivery system for heavy ion treatment was implemented, and simulations of pristine and spread-out Bragg peaks were carried out. Previous studies, focused on specific ion types or single energies, are qualitatively in agreement with the obtained results. Main results. The secondary neutrons energy distributions present a continuous spectrum with two peaks, one centred on the thermal/epithermal region, and one on the high-energy region, with the most probable energy ranging from 19 up to 240 MeV, depending on the ion type and its initial energy. The simulations show that the secondary neutron energies may exceed 400 MeV and, therefore, suitable neutron detectors for this energy range shall be needed. Additionally, the angular distribution of the low energy neutrons is quite isotropic, whereas the fast/relativistic neutrons are mainly scattered in the down-stream direction. Significance. It would be possible to minimize the influence of the heavy ions when measuring the neutron-generated recoil protons by selecting appropriate measurement positions within the phantom. Although there are discrepancies among the three Monte Carlo codes, the results agree qualitatively and in order of magnitude, being sufficient to support further investigations with the ultimate goal of mapping the secondary neutron doses both in- and out-of-field in hadrontherapy. The obtained secondary neutron spectra are available as supplementary material. 
650 4 |a bragg peak 
650 4 |a challenges 
650 4 |a dosimetry 
650 4 |a fluka code 
650 4 |a fragmentation 
650 4 |a high-energy 
650 4 |a ion beam therapy 
650 4 |a Monte Carlo simulations 
650 4 |a nuclear track detectors 
650 4 |a proton therapy 
650 4 |a radiation 
650 4 |a secondary neutrons 
650 4 |a topas 
700 1 |a Geser, Federico A.  |e VerfasserIn  |4 aut 
700 1 |a Muñoz, Iván Domingo  |d 1984-  |e VerfasserIn  |0 (DE-588)1300351586  |0 (DE-627)1858138191  |4 aut 
700 1 |a Stabilini, Alberto  |e VerfasserIn  |4 aut 
700 1 |a Yukihara, Eduardo G.  |e VerfasserIn  |4 aut 
700 1 |a Jäkel, Oliver  |d 1964-  |e VerfasserIn  |0 (DE-588)1050056302  |0 (DE-627)783260709  |0 (DE-576)404358705  |4 aut 
773 0 8 |i Enthalten in  |t Physics in medicine and biology  |d Bristol : IOP Publ., 1956  |g 67(2022), 1, Artikel-ID 015008, Seite 1-18  |h Online-Ressource  |w (DE-627)269016163  |w (DE-600)1473501-5  |w (DE-576)088704130  |x 1361-6560  |7 nnas  |a Assessment of secondary neutrons in particle therapy by Monte Carlo simulations 
773 1 8 |g volume:67  |g year:2022  |g number:1  |g elocationid:015008  |g pages:1-18  |g extent:18  |a Assessment of secondary neutrons in particle therapy by Monte Carlo simulations 
856 4 0 |u https://doi.org/10.1088/1361-6560/ac431b  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=DynamicDOIArticle&SrcApp=WOS&KeyAID=10.1088%2F1361-6560%2Fac431b&DestApp=DOI&SrcAppSID=C6bvvFqkejUrUKINkLa&SrcJTitle=PHYSICS+IN+MEDICINE+AND+BIOLOGY&DestDOIRegistrantName=IOP+Publishing  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20220215 
993 |a Article 
994 |a 2022 
998 |g 1050056302  |a Jäkel, Oliver  |m 1050056302:Jäkel, Oliver  |d 50000  |e 50000PJ1050056302  |k 0/50000/  |p 6  |y j 
998 |g 1251835139  |a Vedelago, José  |m 1251835139:Vedelago, José  |d 50000  |e 50000PV1251835139  |k 0/50000/  |p 6  |y j 
998 |g 1300351586  |a Muñoz, Iván Domingo  |m 1300351586:Muñoz, Iván Domingo  |d 130000  |e 130000PM1300351586  |k 0/130000/  |p 3 
999 |a KXP-PPN1789597854  |e 4059869899 
BIB |a Y 
SER |a journal 
JSO |a {"physDesc":[{"extent":"18 S."}],"recId":"1789597854","origin":[{"dateIssuedKey":"2022","dateIssuedDisp":"17 January 2022"}],"person":[{"family":"Vedelago","role":"aut","given":"José","display":"Vedelago, José"},{"display":"Geser, Federico A.","given":"Federico A.","role":"aut","family":"Geser"},{"display":"Muñoz, Iván Domingo","family":"Muñoz","given":"Iván Domingo","role":"aut"},{"given":"Alberto","role":"aut","family":"Stabilini","display":"Stabilini, Alberto"},{"family":"Yukihara","role":"aut","given":"Eduardo G.","display":"Yukihara, Eduardo G."},{"role":"aut","given":"Oliver","family":"Jäkel","display":"Jäkel, Oliver"}],"relHost":[{"disp":"Assessment of secondary neutrons in particle therapy by Monte Carlo simulationsPhysics in medicine and biology","recId":"269016163","physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Physics in medicine and biology","title":"Physics in medicine and biology","subtitle":"an official journal of the Institute of Physics and Engineering in Medicine"}],"part":{"volume":"67","year":"2022","text":"67(2022), 1, Artikel-ID 015008, Seite 1-18","extent":"18","issue":"1","pages":"1-18"},"id":{"eki":["269016163"],"issn":["1361-6560"],"zdb":["1473501-5"]},"note":["Gesehen am 28.01.2019","Fortsetzung der Druck-Ausgabe"],"language":["eng"],"type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["1.1956 -"],"origin":[{"publisher":"IOP Publ.","dateIssuedKey":"1956","dateIssuedDisp":"1956-","publisherPlace":"Bristol"}]}],"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"note":["Gesehen am 15.02.2022"],"title":[{"title":"Assessment of secondary neutrons in particle therapy by Monte Carlo simulations","title_sort":"Assessment of secondary neutrons in particle therapy by Monte Carlo simulations"}],"name":{"displayForm":["José Vedelago, Federico A. Geser, Iván D. Munoz, Alberto Stabilini, Eduardo G. Yukihara and Oliver Jäkel"]},"id":{"doi":["10.1088/1361-6560/ac431b"],"eki":["1789597854"]}} 
SRT |a VEDELAGOJOASSESSMENT1720