Evolution of salvage radical prostatectomy from open to robotic and further to Retzius sparing surgery

Salvage radical prostatectomy (sRP) has evolved from open to minimally invasive approaches. sRP can be offered to patients with local recurrence to improve biochemical recurrence (BCR)-free and overall survival. We evaluate oncological outcome and continence after retropubic (RRP), conventional (cRA...

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Main Authors: Schütz, Viktoria (Author) , Reimold, Philipp (Author) , Görtz, Magdalena (Author) , Hofer, Luisa (Author) , Dieffenbacher, Svenja (Author) , Nyarangi-Dix, Joanne (Author) , Duensing, Stefan (Author) , Hohenfellner, Markus (Author) , Hatiboglu, Gencay (Author)
Format: Article (Journal)
Language:English
Published: 2022
In: Journal of Clinical Medicine
Year: 2022, Volume: 11, Issue: 1, Pages: 1-10
ISSN:2077-0383
DOI:10.3390/jcm11010202
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.3390/jcm11010202
Verlag, lizenzpflichtig, Volltext: https://www.mdpi.com/2077-0383/11/1/202
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Author Notes:Viktoria Schuetz, Philipp Reimold, Magdalena Goertz, Luisa Hofer, Svenja Dieffenbacher, Joanne Nyarangi-Dix, Stefan Duensing, Markus Hohenfellner and Gencay Hatiboglu

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520 |a Salvage radical prostatectomy (sRP) has evolved from open to minimally invasive approaches. sRP can be offered to patients with local recurrence to improve biochemical recurrence (BCR)-free and overall survival. We evaluate oncological outcome and continence after retropubic (RRP), conventional (cRARP), and Retzius-sparing robotic (rsRARP) surgery. Materials/methods: A total of 53 patients undergoing sRP between 2010 and 2020 were included. Follow-up included oncological outcome and continence. Results: sRP was done as RRP (n = 25), cRARP (n = 7), or rsRARP (n = 21). Median blood loss was 900 mL, 500 mL, and 300 mL for RRP, cRARP, and rsRARP, respectively. At 12 months, 5 (20%), 0, and 4 (19%) patients were continent, 9 (36%), 3 (43%), and 7 (33%) had grade 1 incontinence, 5 (20%), 2 (29%), and 3 (14%) had grade 2 incontinence, and 3 (12%), 2 (29%), and 4 (19%) had grade 3 incontinence for RRP, cRARP, or rsRARP, respectively. During a mean follow-up of 52.6 months, 16 (64%), 4 (57%), and 3 (14%) developed BCR in the RRP-, cRARP-, and rsRARP-group, respectively. Conclusions: Over the years, sRP has shifted from open to laparoscopic/robotic surgery. RARP shows good oncological and functional outcome. rsRARP ensures direct vision on the rectum during preparation and can therefore increase safety and surgeon’s confidence, especially in the salvage setting. 
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