Consistent mutational paths predict eukaryotic thermostability

Proteomes of thermophilic prokaryotes have been instrumental in structural biology and successfully exploited in biotechnology, however many proteins required for eukaryotic cell function are absent from bacteria or archaea. With Chaetomium thermophilum, Thielavia terrestris and Thielavia heterothal...

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Main Authors: Noort, Vera van (Author) , Bradatsch, Bettina (Author) , Arumugam, Manimozhiyan (Author) , Amlacher, Stefan (Author) , Bange, Gert (Author) , Creevey, Chris (Author) , Falk, Sebastian (Author) , Mende, Daniel Richard (Author) , Sinning, Irmgard (Author) , Hurt, Ed (Author) , Bork, Peer (Author)
Format: Article (Journal)
Language:English
Published: 10 January 2013
In: BMC evolutionary biology
Year: 2013, Volume: 13, Pages: 1-13
ISSN:1471-2148
DOI:10.1186/1471-2148-13-7
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/1471-2148-13-7
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Author Notes:Vera van Noort, Bettina Bradatsch, Manimozhiyan Arumugam, Stefan Amlacher, Gert Bange, Chris Creevey, Sebastian Falk, Daniel R. Mende, Irmgard Sinning, Ed Hurt and Peer Bork
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Summary:Proteomes of thermophilic prokaryotes have been instrumental in structural biology and successfully exploited in biotechnology, however many proteins required for eukaryotic cell function are absent from bacteria or archaea. With Chaetomium thermophilum, Thielavia terrestris and Thielavia heterothallica three genome sequences of thermophilic eukaryotes have been published.
Item Description:Gesehen am 21.02.2022
Physical Description:Online Resource
ISSN:1471-2148
DOI:10.1186/1471-2148-13-7