Chlorhexidine and silver-sulfadiazine coated central venous catheters in haematological patients—a double-blind, randomised, prospective, controlled trial

Central venous catheters (CVCs) are essential for the intensive care of patients with haematological illness. Catheter-related infections (CRI) are an important problem in modern medicine, which may lead to life-threatening situations, to prolonged hospitalisation and increased cost. In immunocompro...

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Hauptverfasser: Ostendorf, Torben Armin (VerfasserIn) , Meinhold, Andrea (VerfasserIn) , Harter, Christoph (VerfasserIn) , Salwender, Hans (VerfasserIn) , Egerer, Gerlinde (VerfasserIn) , Geiss, Heinrich K. (VerfasserIn) , Ho, Anthony Dick (VerfasserIn) , Goldschmidt, Hartmut (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 16 April 2005
In: Supportive care in cancer
Year: 2005, Jahrgang: 13, Heft: 12, Pages: 993-1000
ISSN:1433-7339
DOI:10.1007/s00520-005-0812-9
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00520-005-0812-9
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Verfasserangaben:Torben Ostendorf, Andrea Meinhold, Christoph Harter, Hans Salwender, Gerlinde Egerer, Heinrich K. Geiss, Antony D. Ho, Hartmut Goldschmidt

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520 |a Central venous catheters (CVCs) are essential for the intensive care of patients with haematological illness. Catheter-related infections (CRI) are an important problem in modern medicine, which may lead to life-threatening situations, to prolonged hospitalisation and increased cost. In immunocompromised patients suffering from haemato-oncological diseases, CRI is a significant factor for adverse outcome. Several clinical studies have shown that CVCs coated with antiseptics such as chlorhexidine and silver-sulfadiazine (CHSS) reduce the risk of catheter-related bacteraemia. Most studies, however, were performed on intensive care patients not suffering from chemotherapy-induced immunosuppression. 
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