Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

Aberrant Wnt signalling, regulating cell development and stemness, influences the development of many cancer types. The Aryl hydrocarbon receptor (AhR) mediates tumorigenesis of environmental pollutants. Complex interaction patterns of genes assigned to AhR/Wnt-signalling were recently associated wi...

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Main Authors: Rosenberger, Albert (Author) , Muttray, Nils (Author) , Hung, Rayjean J. (Author) , Christiani, David C. (Author) , Caporaso, Neil E. (Author) , Liu, Geoffrey (Author) , Bojesen, Stig E. (Author) , Le Marchand, Loic (Author) , Albanes, Demetrios (Author) , Aldrich, Melinda C. (Author) , Tardon, Adonina (Author) , Fernández-Tardón, Guillermo (Author) , Rennert, Gad (Author) , Field, John K. (Author) , Davies, Michael P. A. (Author) , Liloglou, Triantafillos (Author) , Kiemeney, Lambertus A. (Author) , Lazarus, Philip (Author) , Wendel, Bernadette (Author) , Haugen, Aage (Author) , Zienolddiny, Shanbeh (Author) , Lam, Stephen (Author) , Schabath, Matthew B. (Author) , Andrew, Angeline S. (Author) , Duell, Eric J. (Author) , Arnold, Susanne M. (Author) , Goodman, Gary E. (Author) , Chen, Chu (Author) , Doherty, Jennifer A. (Author) , Taylor, Fiona (Author) , Cox, Angela (Author) , Woll, Penella J. (Author) , Risch, Angela (Author) , Muley, Thomas (Author) , Johansson, Mikael (Author) , Brennan, Paul (Author) , Landi, Maria Teresa (Author) , Shete, Sanjay S. (Author) , Amos, Christopher I. (Author) , Bickeböller, Heike (Author)
Format: Article (Journal)
Language:English
Published: 31 January 2022
In: European journal of medical research
Year: 2022, Volume: 27, Pages: 1-13
ISSN:2047-783X
DOI:10.1186/s40001-022-00638-7
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s40001-022-00638-7
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Author Notes:Albert Rosenberger, Nils Muttray, Rayjean J. Hung, David C. Christiani, Neil E. Caporaso, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Melinda C. Aldrich, Adonina Tardon, Guillermo Fernández-Tardón, Gad Rennert, John K. Field, Michael P. A. Davies, Triantafillos Liloglou, Lambertus A. Kiemeney, Philip Lazarus, Bernadette Wendel, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Eric J. Duell, Susanne M. Arnold, Gary E. Goodman, Chu Chen, Jennifer A. Doherty, Fiona Taylor, Angela Cox, Penella J. Woll, Angela Risch, Thomas R. Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Sanjay S. Shete, Christopher I. Amos, Heike Bickeböller and The INTEGRAL-ILCCO Consortium
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Summary:Aberrant Wnt signalling, regulating cell development and stemness, influences the development of many cancer types. The Aryl hydrocarbon receptor (AhR) mediates tumorigenesis of environmental pollutants. Complex interaction patterns of genes assigned to AhR/Wnt-signalling were recently associated with lung cancer susceptibility.
Item Description:Gesehen am 16.03.2022
Physical Description:Online Resource
ISSN:2047-783X
DOI:10.1186/s40001-022-00638-7