Buchumschlag

Racial and socioeconomic disparity associates with differences in cardiac DNA methylation among men with end-stage heart failure

Heart failure (HF) is a multifactorial syndrome that remains a leading cause of worldwide morbidity. Despite its high prevalence, only half of patients with HF respond to guideline-directed medical management, prompting therapeutic efforts to confront the molecular underpinnings of its heterogeneity...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pepin, Mark (VerfasserIn) , Ha, Chae-Myeong (VerfasserIn) , Potter, Luke A. (VerfasserIn) , Bakshi, Sayan (VerfasserIn) , Barchue, Joseph P. (VerfasserIn) , Haj Asaad, Ayman (VerfasserIn) , Pogwizd, Steven M. (VerfasserIn) , Pamboukian, Salpy V. (VerfasserIn) , Hidalgo, Bertha A. (VerfasserIn) , Vickers, Selwyn M. (VerfasserIn) , Wende, Adam R. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: March 26, 2021
In: American journal of physiology. Heart and circulatory physiology
Year: 2021, Jahrgang: 320, Heft: 5, Pages: H2066-H2079
ISSN:1522-1539
DOI:10.1152/ajpheart.00036.2021
Online-Zugang:Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.1152/ajpheart.00036.2021
Verlag, lizenzpflichtig, Volltext: https://journals.physiology.org/doi/full/10.1152/ajpheart.00036.2021
Volltext
Verfasserangaben:Mark E. Pepin, Chae-Myeong Ha, Luke A. Potter, Sayan Bakshi, Joseph P. Barchue, Ayman Haj Asaad, Steven M. Pogwizd, Salpy V. Pamboukian, Bertha A. Hidalgo, Selwyn M. Vickers, Adam R. Wende
Beschreibung
Zusammenfassung:Heart failure (HF) is a multifactorial syndrome that remains a leading cause of worldwide morbidity. Despite its high prevalence, only half of patients with HF respond to guideline-directed medical management, prompting therapeutic efforts to confront the molecular underpinnings of its heterogeneity. In the current study, we examined epigenetics as a yet unexplored source of heterogeneity among patients with end-stage HF.
Beschreibung:Gesehen am 17.03.2022
Beschreibung:Online Resource
ISSN:1522-1539
DOI:10.1152/ajpheart.00036.2021

Ähnliche Einträge