PCDH10 is a candidate tumour suppressor gene in medulloblastoma

The aim of this study was to investigate the genetic and epigenetic mechanisms contributing to PCDH10 down-regulation in medulloblastoma. We examined the role of PCDH10 as a mediator of medulloblastoma cell proliferation, cell cycle progression, and cell migration.

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Bibliographic Details
Main Authors: Bertrand, Kelsey C. (Author) , Mack, Stephen C. (Author) , Northcott, Paul A. (Author) , Garzia, Livia (Author) , Dubuc, Adrian (Author) , Pfister, Stefan (Author) , Rutka, James T. (Author) , Weiss, William A. (Author) , Taylor, Michael D. (Author)
Format: Article (Journal)
Language:English
Published: 20 May 2011
In: Child's nervous system
Year: 2011, Volume: 27, Issue: 8, Pages: 1243-1249
ISSN:1433-0350
DOI:10.1007/s00381-011-1486-x
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00381-011-1486-x
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Author Notes:Kelsey C. Bertrand, Stephen C. Mack, Paul A. Northcott, Livia Garzia, Adrian Dubuc, Stefan M. Pfister, James T. Rutka, William A. Weiss, Michael D. Taylor
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Summary:The aim of this study was to investigate the genetic and epigenetic mechanisms contributing to PCDH10 down-regulation in medulloblastoma. We examined the role of PCDH10 as a mediator of medulloblastoma cell proliferation, cell cycle progression, and cell migration.
Item Description:Gesehen am 23.03.2022
Physical Description:Online Resource
ISSN:1433-0350
DOI:10.1007/s00381-011-1486-x