Designing a sequential Ugi/Ullmann type reaction for the synthesis of indolo(1,2-a)quinoxalinones catalyzed by CuI/l-proline
An efficient strategy for the one-pot syntheses of indolo[1,2-a]quinoxalinones catalyzed by CuI have been developed. The procedures combine the Ugi four-component reaction of aldehydes, 2-iodoaniline, 2-indole carboxylic acid, and isocyanides followed by the copper-catalyzed intramolecular N-arylati...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 July 2011
|
| In: |
Tetrahedron
Year: 2011, Jahrgang: 67, Heft: 38, Pages: 7294-7300 |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2011.07.052 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tet.2011.07.052 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S004040201101091X 
|
| Verfasserangaben: | Saeed Balalaie, Morteza Bararjanian, Saeedeh Hosseinzadeh, Frank Rominger, Hamid Reza Bijanzadeh, Eckardt Wolf |
| Zusammenfassung: | An efficient strategy for the one-pot syntheses of indolo[1,2-a]quinoxalinones catalyzed by CuI have been developed. The procedures combine the Ugi four-component reaction of aldehydes, 2-iodoaniline, 2-indole carboxylic acid, and isocyanides followed by the copper-catalyzed intramolecular N-arylation of the Ugi product in one-pot procedure, which afford the desired products in good to very good yields. |
|---|---|
| Beschreibung: | Gesehen am 25.03.2022 Im Titel ist der Ausdruck "1,2-a" eckig geklammert |
| Beschreibung: | Online Resource |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2011.07.052 |