Designing a sequential Ugi/Ullmann type reaction for the synthesis of indolo(1,2-a)quinoxalinones catalyzed by CuI/l-proline
An efficient strategy for the one-pot syntheses of indolo[1,2-a]quinoxalinones catalyzed by CuI have been developed. The procedures combine the Ugi four-component reaction of aldehydes, 2-iodoaniline, 2-indole carboxylic acid, and isocyanides followed by the copper-catalyzed intramolecular N-arylati...
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| Hauptverfasser: | , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 July 2011
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| In: |
Tetrahedron
Year: 2011, Jahrgang: 67, Heft: 38, Pages: 7294-7300 |
| ISSN: | 1464-5416 |
| DOI: | 10.1016/j.tet.2011.07.052 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.tet.2011.07.052 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S004040201101091X 
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| Verfasserangaben: | Saeed Balalaie, Morteza Bararjanian, Saeedeh Hosseinzadeh, Frank Rominger, Hamid Reza Bijanzadeh, Eckardt Wolf |
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| 520 | |a An efficient strategy for the one-pot syntheses of indolo[1,2-a]quinoxalinones catalyzed by CuI have been developed. The procedures combine the Ugi four-component reaction of aldehydes, 2-iodoaniline, 2-indole carboxylic acid, and isocyanides followed by the copper-catalyzed intramolecular N-arylation of the Ugi product in one-pot procedure, which afford the desired products in good to very good yields. | ||
| 650 | 4 | |a CuI/-Proline catalyst | |
| 650 | 4 | |a Indolo(1,2-)quinoxalinones | |
| 650 | 4 | |a One-pot procedure | |
| 650 | 4 | |a Ugi reaction | |
| 650 | 4 | |a Ullmann reaction | |
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