Radiolabeled heterobivalent peptidic ligands: an approach with high future potential for in vivo imaging and therapy of malignant diseases

Two-pronged synergism: We review the recently developed approach of using heterobivalent peptide ligands that interact concomitantly with different receptors on tumor cells. These ligands exhibit highly favorable tumor-targeting properties and pave the way for the development of drugs for specific,...

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Hauptverfasser: Fischer, Gabriel (VerfasserIn) , Schirrmacher, Ralf (VerfasserIn) , Wängler, Björn (VerfasserIn) , Wängler, Carmen (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 05 April 2013
In: ChemMedChem
Year: 2013, Jahrgang: 8, Heft: 6, Pages: 883-890
ISSN:1860-7187
DOI:10.1002/cmdc.201300081
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1002/cmdc.201300081
Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/cmdc.201300081
Volltext
Verfasserangaben:Gabriel Fischer, Ralf Schirrmacher, Björn Wängler, and Carmen Wängler
Beschreibung
Zusammenfassung:Two-pronged synergism: We review the recently developed approach of using heterobivalent peptide ligands that interact concomitantly with different receptors on tumor cells. These ligands exhibit highly favorable tumor-targeting properties and pave the way for the development of drugs for specific, sensitive, and noninvasive tumor imaging and therapy.
Beschreibung:Gesehen am 31.03.2022
Beschreibung:Online Resource
ISSN:1860-7187
DOI:10.1002/cmdc.201300081