Ultralarge von Willebrand factor fibers mediate luminal staphylococcus aureus adhesion to an intact endothelial cell layer under shear stress
Background— - - During pathogenesis of infective endocarditis, Staphylococcus aureus adherence often occurs without identifiable preexisting heart disease. However, molecular mechanisms mediating initial bacterial adhesion to morphologically intact endocardium are largely unknown. - - Methods and...
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| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
29 May 2013
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| In: |
Circulation
Year: 2013, Volume: 128, Issue: 1, Pages: 50-59 |
| ISSN: | 1524-4539 |
| DOI: | 10.1161/CIRCULATIONAHA.113.002008 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1161/CIRCULATIONAHA.113.002008 Verlag, lizenzpflichtig, Volltext: https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.002008 |
| Author Notes: | Karin I. Pappelbaum, MSc, Christian Gorzelanny, PhD, Sandra Grässle, MSc, Jan Suckau, Matthias W. Laschke, MD, PhD, Markus Bischoff, PhD, Corinne Bauer, Cand. Med, Marina Schorpp-Kistner, PhD, Christopher Weidenmaier, PhD, Reinhard Schneppenheim, MD, PhD, Tobias Obser, BTA, Bhanu Sinha, MD, PhD, and Stefan W. Schneider, MD |