Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats
Alterations of the glutamatergic system have been implicated in the pathophysiology and treatment of major depression. In order to investigate the expression and function of mGlu5 receptors in an animal model for treatment-resistant depression we used rats bred for congenital learned helplessness (c...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Article (Journal) |
| Lenguaje: | inglés |
| Publicado: |
March 2013
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| In: |
Neuropharmacology
Year: 2013, Volumen: 66, Pages: 339-347 |
| ISSN: | 1873-7064 |
| DOI: | 10.1016/j.neuropharm.2012.05.046 |
| Acceso en línea: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.neuropharm.2012.05.046 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0028390812002547 
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| Notas de Autor: | Marco Pignatelli, Barbara Vollmayr, Sophie Helene Richter, Silvia Middei, Francesco Matrisciano, Gemma Molinaro, Carla Nasca, Giuseppe Battaglia, Martine Ammassari-Teule, Marco Feligioni, Robert Nisticò, Ferdinando Nicoletti, Peter Gass |