Development of methodology for assessing steroid-tapering in clinical trials for biologics in asthma

Long-term use of oral corticosteroids (OCS) is associated with a risk of adverse events and comorbidities. As such, a goal in assessing the efficacy of biologics in severe asthma is often to monitor reduction in OCS usage. Importantly, however, OCS dose reductions must be conducted without loss of d...

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Hauptverfasser: Korn, Stephanie (VerfasserIn) , Howarth, Peter (VerfasserIn) , Smith, Steven G. (VerfasserIn) , Price, Robert G. (VerfasserIn) , Yancey, Steven W. (VerfasserIn) , Prazma, Charlene M. (VerfasserIn) , Bel, Elisabeth H. (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 04 March 2022
In: Respiratory research
Year: 2022, Jahrgang: 23, Pages: 1-9
ISSN:1465-993X
DOI:10.1186/s12931-022-01959-1
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1186/s12931-022-01959-1
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Verfasserangaben:Stephanie Korn, Peter Howarth, Steven G. Smith, Robert G. Price, Steven W. Yancey, Charlene M. Prazma and Elisabeth H. Bel

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650 4 |a Asthma 
650 4 |a Biologics 
650 4 |a Efficacy 
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