Immune reactions to Listeria monocytogenes in the brain

Listeria monocytogenes (LM) is a common pathogen of cerebral infections. Experimental studies in mice have revealed that epithelial cells of the choroid plexus, ependymal cells, macrophages/microglia, and neurons are the target cells of LM. For the intracerebral pathogenesis of LM cell-to-cell sprea...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Schlüter, Dirk (VerfasserIn) , Buck, Christine (VerfasserIn) , Reiter, Sabine (VerfasserIn) , Meyer, Timothy (VerfasserIn) , Hof, Herbert (VerfasserIn) , Deckert-Schlüter, Martina (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1999
In: Immunobiology
Year: 1999, Jahrgang: 201, Heft: 2, Pages: 188-195
ISSN:1878-3279
DOI:10.1016/S0171-2985(99)80058-8
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0171-2985(99)80058-8
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0171298599800588
Volltext
Verfasserangaben:Dirk Schlüter, Christine Buck, Sabine Reiter, Timothy Meyer, Herbert Hof, Martina Deckert-Schlüter

MARC

LEADER 00000caa a2200000 c 4500
001 1797746154
003 DE-627
005 20230428015053.0
007 cr uuu---uuuuu
008 220406s1999 xx |||||o 00| ||eng c
024 7 |a 10.1016/S0171-2985(99)80058-8  |2 doi 
035 |a (DE-627)1797746154 
035 |a (DE-599)KXP1797746154 
035 |a (OCoLC)1341458524 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Schlüter, Dirk  |d 1964-  |e VerfasserIn  |0 (DE-588)1077201079  |0 (DE-627)836115821  |0 (DE-576)169692418  |4 aut 
245 1 0 |a Immune reactions to Listeria monocytogenes in the brain  |c Dirk Schlüter, Christine Buck, Sabine Reiter, Timothy Meyer, Herbert Hof, Martina Deckert-Schlüter 
264 1 |c 1999 
300 |a 8 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Elektronische Reproduktion der Druck-Ausgabe 1 November 2011 
500 |a Gesehen am 06.04.2022 
520 |a Listeria monocytogenes (LM) is a common pathogen of cerebral infections. Experimental studies in mice have revealed that epithelial cells of the choroid plexus, ependymal cells, macrophages/microglia, and neurons are the target cells of LM. For the intracerebral pathogenesis of LM cell-to-cell spread via phospholipase C was particularly important. However, phospholipase C-deficient LM were not completely attenuated and, therefore, other virulence factors may also contribute to the intracerebral spread of LM. In general, all mice suffering from cerebral listeriosis rapidly succumbed to the disease. Active systemic immunization prior to intracerebral infection reduced the mortality rate to 40%. The favorable prognosis of immunized mice correlated with a reduced intracerebral bacterial load, an increased recruitment of protective CD4+ and CD8+ T cells as well as an upregulated mRNA production of protective cytokines. 
700 1 |a Buck, Christine  |e VerfasserIn  |4 aut 
700 1 |a Reiter, Sabine  |e VerfasserIn  |4 aut 
700 1 |a Meyer, Timothy  |d 1967-  |e VerfasserIn  |0 (DE-588)122795822  |0 (DE-627)706047087  |0 (DE-576)293424144  |4 aut 
700 1 |a Hof, Herbert  |e VerfasserIn  |0 (DE-588)1050912535  |0 (DE-627)785282548  |0 (DE-576)405358393  |4 aut 
700 1 |a Deckert-Schlüter, Martina  |e VerfasserIn  |4 aut 
773 0 8 |i Enthalten in  |t Immunobiology  |d München : Elsevier, 1979  |g 201(1999), 2, Seite 188-195  |h Online-Ressource  |w (DE-627)335415989  |w (DE-600)2060227-3  |w (DE-576)096290919  |x 1878-3279  |7 nnas  |a Immune reactions to Listeria monocytogenes in the brain 
773 1 8 |g volume:201  |g year:1999  |g number:2  |g pages:188-195  |g extent:8  |a Immune reactions to Listeria monocytogenes in the brain 
856 4 0 |u https://doi.org/10.1016/S0171-2985(99)80058-8  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
856 4 0 |u https://www.sciencedirect.com/science/article/pii/S0171298599800588  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20220406 
994 |a 1999 
998 |g 1050912535  |a Hof, Herbert  |m 1050912535:Hof, Herbert  |d 60000  |d 63200  |e 60000PH1050912535  |e 63200PH1050912535  |k 0/60000/  |k 1/60000/63200/  |p 5 
998 |g 122795822  |a Meyer, Timothy  |m 122795822:Meyer, Timothy  |d 60000  |d 63200  |e 60000PM122795822  |e 63200PM122795822  |k 0/60000/  |k 1/60000/63200/  |p 4 
998 |g 1077201079  |a Schlüter, Dirk  |m 1077201079:Schlüter, Dirk  |d 60000  |d 63200  |e 60000PS1077201079  |e 63200PS1077201079  |k 0/60000/  |k 1/60000/63200/  |p 1  |x j 
999 |a KXP-PPN1797746154  |e 4112456891 
BIB |a Y 
SER |a journal 
JSO |a {"title":[{"title":"Immune reactions to Listeria monocytogenes in the brain","title_sort":"Immune reactions to Listeria monocytogenes in the brain"}],"person":[{"given":"Dirk","family":"Schlüter","role":"aut","roleDisplay":"VerfasserIn","display":"Schlüter, Dirk"},{"family":"Buck","given":"Christine","display":"Buck, Christine","roleDisplay":"VerfasserIn","role":"aut"},{"role":"aut","display":"Reiter, Sabine","roleDisplay":"VerfasserIn","given":"Sabine","family":"Reiter"},{"given":"Timothy","family":"Meyer","role":"aut","roleDisplay":"VerfasserIn","display":"Meyer, Timothy"},{"role":"aut","display":"Hof, Herbert","roleDisplay":"VerfasserIn","given":"Herbert","family":"Hof"},{"given":"Martina","family":"Deckert-Schlüter","role":"aut","display":"Deckert-Schlüter, Martina","roleDisplay":"VerfasserIn"}],"note":["Elektronische Reproduktion der Druck-Ausgabe 1 November 2011","Gesehen am 06.04.2022"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"recId":"1797746154","language":["eng"],"origin":[{"dateIssuedKey":"1999","dateIssuedDisp":"1999"}],"id":{"doi":["10.1016/S0171-2985(99)80058-8"],"eki":["1797746154"]},"name":{"displayForm":["Dirk Schlüter, Christine Buck, Sabine Reiter, Timothy Meyer, Herbert Hof, Martina Deckert-Schlüter"]},"physDesc":[{"extent":"8 S."}],"relHost":[{"recId":"335415989","language":["eng"],"note":["Gesehen am 12.02.20"],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Immune reactions to Listeria monocytogenes in the brainImmunobiology","part":{"extent":"8","text":"201(1999), 2, Seite 188-195","volume":"201","pages":"188-195","issue":"2","year":"1999"},"pubHistory":["156.1979/80,4 -"],"title":[{"title":"Immunobiology","subtitle":"experimental and clinical","title_sort":"Immunobiology"}],"physDesc":[{"extent":"Online-Ressource"}],"id":{"issn":["1878-3279"],"zdb":["2060227-3"],"eki":["335415989"]},"origin":[{"publisher":"Elsevier ; Urban & Fischer","dateIssuedKey":"1979","dateIssuedDisp":"1979-","publisherPlace":"München ; Jena"}]}]} 
SRT |a SCHLUETERDIMMUNEREAC1999