The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability
Cancer evolution depends on epigenetic and genetic diversity. Historically, in multiple myeloma (MM), subclonal diversity and tumor evolution have been investigated mostly from a genetic perspective.
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| Hauptverfasser: | , , , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 August 2021
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| In: |
Genome medicine
Year: 2021, Jahrgang: 13, Pages: 1-21 |
| ISSN: | 1756-994X |
| DOI: | 10.1186/s13073-021-00938-3 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s13073-021-00938-3 |
| Verfasserangaben: | Jennifer Derrien, Catherine Guérin-Charbonnel, Victor Gaborit, Loïc Campion, Magali Devic, Elise Douillard, Nathalie Roi, Hervé Avet-Loiseau, Olivier Decaux, Thierry Facon, Jan-Philipp Mallm, Roland Eils, Nikhil C. Munshi, Philippe Moreau, Carl Herrmann, Florence Magrangeas and Stéphane Minvielle |
| Zusammenfassung: | Cancer evolution depends on epigenetic and genetic diversity. Historically, in multiple myeloma (MM), subclonal diversity and tumor evolution have been investigated mostly from a genetic perspective. |
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| Beschreibung: | Gesehen am 14.04.2022 |
| Beschreibung: | Online Resource |
| ISSN: | 1756-994X |
| DOI: | 10.1186/s13073-021-00938-3 |