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p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth

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Absence of the leucine zipper transcription factor p45NF-E2 results in thrombocytopenia, impaired placental vascularization and intrauterine growth restriction (IUGR) in mice. The mechanism underlying the p45NF-E2-dependent placental defect and IUGR remains unknown. Here, we show that the placental...

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Main Authors: Kashif, Muhammed (Author) , Hellwig, Andrea (Author) , Kolleker, Alexander (Author) , Shahzad Hussain, Khurrum (Author) , Wang, Hongjie (Author) , Lang, Siegfried (Author) , Wolter, Juliane (Author) , Madhusudhan, Thati (Author) , Vinnikov, Ilya A. (Author) , Bierhaus, Angelika (Author) , Nawroth, Peter Paul (Author) , Isermann, Berend (Author)
Format: Article (Journal)
Language:English
Published: June 2011
In: Development
Year: 2011, Volume: 138, Issue: 11, Pages: 2235-2247
ISSN:1477-9129
DOI:10.1242/dev.059105
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1242/dev.059105
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Author Notes:Muhammed Kashif, Andrea Hellwig, Alexandre Kolleker, Khurrum Shahzad, Hongjie Wang, Siegfried Lang, Juliane Wolter, Madhusudhan Thati, Ilya Vinnikov, Angelika Bierhaus, Peter P. Nawroth, Berend Isermann
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p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth by Kashif, Muhammed (Author) , Hellwig, Andrea (Author) , Kolleker, Alexander (Author) ,


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