Protein C concentrate controls leukocyte recruitment during inflammation and improves survival during endotoxemia after efficient in vivo activation
Anti-inflammatory properties of protein C (PC) concentrate are poorly studied compared to activated protein C, although PC is suggested to be safer in clinical use. We investigated how PC interferes with the leukocyte recruitment cascade during acute inflammation and its efficacy during murine endot...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
8 September 2011
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| In: |
The American journal of pathology
Year: 2011, Jahrgang: 179, Heft: 5, Pages: 2637-2650 |
| ISSN: | 1525-2191 |
| DOI: | 10.1016/j.ajpath.2011.07.023 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ajpath.2011.07.023 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0002944011007425 |
| Verfasserangaben: | David Frommhold, Julia Tschada, Natascha Braach, Kirsten Buschmann, Axel Doerner, Johanna Pflaum, Marie-Sophie Stahl, Hongjie Wang, Lutz Koch, Markus Sperandio, Angelika Bierhaus, Berend Isermann, and Johannes Poeschl |