Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation

In late puberty, estrogen decelerates bone growth by stimulating growth plate maturation. In this study, we analyzed the mechanism of estrogen action using two pubertal growth plate specimens of one girl at Tanner stage B2 and Tanner stage B3. Histological analysis showed that progression of puberty...

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Main Authors: Emons, Joyce (Author) , Dutilh, Bas E. (Author) , Decker, Eva (Author) , Pirzer, Heide (Author) , Sticht, Carsten (Author) , Gretz, Norbert (Author) , Rappold, Gudrun (Author) , Cameron, Ewan R. (Author) , Neil, James C. (Author) , Stein, Gary S. (Author) , Wijnen, Andre J. van (Author) , Wit, Jan Maarten (Author) , Post, Janine N. (Author) , Karperien, Marcel (Author)
Format: Article (Journal)
Language:English
Published: May 2011
In: The journal of endocrinology
Year: 2011, Volume: 209, Issue: 2, Pages: 245-254
ISSN:1479-6805
DOI:10.1530/JOE-10-0219
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1530/JOE-10-0219
Verlag, lizenzpflichtig, Volltext: https://joe.bioscientifica.com/view/journals/joe/209/2/245.xml
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Author Notes:Joyce Emons, Bas E. Dutilh, Eva Decker, Heide Pirzer, Carsten Sticht, Norbert Gretz, Gudrun Rappold, Ewan R. Cameron, James C. Neil, Gary S. Stein, Andre J. van Wijnen, Jan Maarten Wit, Janine N. Post and Marcel Karperien