Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups
HSP 27, a marker of differentiation and proliferation, helps the cell in repair processes after environmental stress such as heat, UV-irradiation and oxidative stress. So far, its role on carcinogenesis is not yet understood. HSP 27 was studied immunohistochemically in different types of primary, un...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
June 1999
|
| In: |
European journal of dermatology
Year: 1999, Jahrgang: 9, Heft: 4, Pages: 281-284 |
| ISSN: | 1952-4013 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: http://www.jle.com/en/revues/ejd/e-docs/heat_shock_protein_hsp_27_is_expressed_in_all_types_of_basal_cell_carcinoma_in_low_and_high_risk_uv_exposure_groups_100092/article.phtml?tab=texte
|
| Verfasserangaben: | C. Bayerl, B. Dorfner, B. Rzany, E. Fuhrmann, C.C. Coelho, E.G. Jung |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1803957654 | ||
| 003 | DE-627 | ||
| 005 | 20220820185427.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220519s1999 xx |||||o 00| ||eng c | ||
| 035 | |a (DE-627)1803957654 | ||
| 035 | |a (DE-599)KXP1803957654 | ||
| 035 | |a (OCoLC)1341460327 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Bayerl, Christiane |e VerfasserIn |0 (DE-588)1019104147 |0 (DE-627)690775083 |0 (DE-576)168366592 |4 aut | |
| 245 | 1 | 0 | |a Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups |c C. Bayerl, B. Dorfner, B. Rzany, E. Fuhrmann, C.C. Coelho, E.G. Jung |
| 264 | 1 | |c June 1999 | |
| 300 | |a 4 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 19.05.2022 | ||
| 520 | |a HSP 27, a marker of differentiation and proliferation, helps the cell in repair processes after environmental stress such as heat, UV-irradiation and oxidative stress. So far, its role on carcinogenesis is not yet understood. HSP 27 was studied immunohistochemically in different types of primary, untreated basal cell carcinoma (BCC) in two populations with different UV exposure habits: descendents from Germany, “Pommern”, living in Brazil (Pommeranos, n = 15), rural workers with high UV exposure and Germans from the region Baden-Württemberg with indoor jobs (n = 14). Age distribution and type of BCC were similar between the Pommeranos and the Germans. Specimens of BCC (n = 15 solid, n = 6 keratotic, n = 4 adenoid, n = 4 fibrotic) were evaluated in cryostat and paraffin sections for HSP 27, HSP 72 and bcl-2. In Pommeranos in Brazil (UV high risk group) versus (vs) inhabitants from Baden-Württemberg (UV low risk group), HSP 27 was expressed in 93% vs 79% in all histological subclasses, HSP 72 in 20% vs 21% and bcl-2 in 93 % in both groups. Antibodies against HSP 27, but not HSP 72, labeled BCC of all types. In contrast to the lack of HSP 27 in squamous cell carcinoma reported in the literature, we found HSP 27 and bcl-2 positive cells in BCC which might characterize the tumour as relatively benign and slow progressing. | ||
| 700 | 1 | |a Dorfner, Bettina |d 1972- |e VerfasserIn |0 (DE-588)121842460 |0 (DE-627)705674096 |0 (DE-576)292913583 |4 aut | |
| 700 | 1 | |a Rzany, Berthold |e VerfasserIn |0 (DE-588)111938961 |0 (DE-627)516471902 |0 (DE-576)170153975 |4 aut | |
| 700 | 1 | |a Fuhrmann, E. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Coelho, C. C. |e VerfasserIn |4 aut | |
| 700 | 1 | |a Jung, Ernst G. |d 1932-2023 |e VerfasserIn |0 (DE-588)107312484 |0 (DE-627)528668838 |0 (DE-576)161620337 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t European journal of dermatology |d Montrouge : Libbey Eurotext, 1997 |g 9(1999), 4, Seite 281-284 |h Online-Ressource |w (DE-627)326644733 |w (DE-600)2041476-6 |w (DE-576)098841475 |x 1952-4013 |7 nnas |a Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups |
| 773 | 1 | 8 | |g volume:9 |g year:1999 |g number:4 |g pages:281-284 |g extent:4 |a Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups |
| 856 | 4 | 0 | |u http://www.jle.com/en/revues/ejd/e-docs/heat_shock_protein_hsp_27_is_expressed_in_all_types_of_basal_cell_carcinoma_in_low_and_high_risk_uv_exposure_groups_100092/article.phtml?tab=texte |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220519 | ||
| 993 | |a Article | ||
| 994 | |a 1999 | ||
| 998 | |g 107312484 |a Jung, Ernst G. |m 107312484:Jung, Ernst G. |d 60000 |e 60000PJ107312484 |k 0/60000/ |p 6 |y j | ||
| 998 | |g 111938961 |a Rzany, Berthold |m 111938961:Rzany, Berthold |d 60000 |d 61900 |e 60000PR111938961 |e 61900PR111938961 |k 0/60000/ |k 1/60000/61900/ |p 3 | ||
| 998 | |g 121842460 |a Dorfner, Bettina |m 121842460:Dorfner, Bettina |d 60000 |d 61900 |e 60000PD121842460 |e 61900PD121842460 |k 0/60000/ |k 1/60000/61900/ |p 2 | ||
| 998 | |g 1019104147 |a Bayerl, Christiane |m 1019104147:Bayerl, Christiane |d 60000 |d 61900 |e 60000PB1019104147 |e 61900PB1019104147 |k 0/60000/ |k 1/60000/61900/ |p 1 |x j | ||
| 999 | |a KXP-PPN1803957654 |e 4136351402 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"role":"aut","roleDisplay":"VerfasserIn","display":"Bayerl, Christiane","given":"Christiane","family":"Bayerl"},{"display":"Dorfner, Bettina","roleDisplay":"VerfasserIn","role":"aut","family":"Dorfner","given":"Bettina"},{"display":"Rzany, Berthold","roleDisplay":"VerfasserIn","role":"aut","family":"Rzany","given":"Berthold"},{"display":"Fuhrmann, E.","roleDisplay":"VerfasserIn","role":"aut","family":"Fuhrmann","given":"E."},{"family":"Coelho","given":"C. C.","display":"Coelho, C. C.","roleDisplay":"VerfasserIn","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Jung, Ernst G.","role":"aut","family":"Jung","given":"Ernst G."}],"title":[{"title_sort":"Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups","title":"Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groups"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Gesehen am 19.05.2022"],"language":["eng"],"recId":"1803957654","name":{"displayForm":["C. Bayerl, B. Dorfner, B. Rzany, E. Fuhrmann, C.C. Coelho, E.G. Jung"]},"origin":[{"dateIssuedDisp":"June 1999","dateIssuedKey":"1999"}],"id":{"eki":["1803957654"]},"physDesc":[{"extent":"4 S."}],"relHost":[{"title":[{"title":"European journal of dermatology","subtitle":"EJD","title_sort":"European journal of dermatology"}],"type":{"media":"Online-Ressource","bibl":"periodical"},"disp":"Heat shock protein HSP 27 is expressed in all types of basal cell carcinoma in low and high risk UV exposure groupsEuropean journal of dermatology","note":["Gesehen am 19.02.25"],"recId":"326644733","language":["eng"],"pubHistory":["Nachgewiesen 7.1997 -"],"titleAlt":[{"title":"EJD"}],"part":{"pages":"281-284","issue":"4","year":"1999","extent":"4","volume":"9","text":"9(1999), 4, Seite 281-284"},"origin":[{"publisher":"Libbey Eurotext","dateIssuedKey":"1997","dateIssuedDisp":"1997-","publisherPlace":"Montrouge"}],"id":{"issn":["1952-4013"],"eki":["326644733"],"zdb":["2041476-6"]},"physDesc":[{"extent":"Online-Ressource"}]}]} | ||
| SRT | |a BAYERLCHRIHEATSHOCKP1999 | ||