Unknown onset stroke: differences between patients with wake-up stroke and daytime-unwitnessed stroke
Objectives - Patients with unknown onset stroke (UOS) can be categorized as wake-up stroke (WUS) and daytime-unwitnessed stroke (DUS). We sought to determine whether decisions for initial imaging modalities, frequency of mismatch findings, resulting treatment decisions and outcome differ between WUS...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 2021
|
| In: |
Journal of stroke and cerebrovascular diseases
Year: 2021, Volume: 30, Issue: 7, Pages: 1-6 |
| ISSN: | 1532-8511 |
| DOI: | 10.1016/j.jstrokecerebrovasdis.2021.105842 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105842 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1052305721002457 
|
| Author Notes: | Katharina Vedder, Dr. Anne Ebert, Prof. Dr. Kristina Szabo, Prof. Dr. Alex Förster, and Prof. Dr. Angelika Alonso |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1804096741 | ||
| 003 | DE-627 | ||
| 005 | 20240416193524.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 220523s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.jstrokecerebrovasdis.2021.105842 |2 doi | |
| 035 | |a (DE-627)1804096741 | ||
| 035 | |a (DE-599)KXP1804096741 | ||
| 035 | |a (OCoLC)1341460290 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Vedder, Katharina |d 1996- |e VerfasserIn |0 (DE-588)1258185857 |0 (DE-627)180408946X |4 aut | |
| 245 | 1 | 0 | |a Unknown onset stroke |b differences between patients with wake-up stroke and daytime-unwitnessed stroke |c Katharina Vedder, Dr. Anne Ebert, Prof. Dr. Kristina Szabo, Prof. Dr. Alex Förster, and Prof. Dr. Angelika Alonso |
| 264 | 1 | |c July 2021 | |
| 300 | |a 6 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 23.05.2022 | ||
| 520 | |a Objectives - Patients with unknown onset stroke (UOS) can be categorized as wake-up stroke (WUS) and daytime-unwitnessed stroke (DUS). We sought to determine whether decisions for initial imaging modalities, frequency of mismatch findings, resulting treatment decisions and outcome differ between WUS and DUS patients. - Materials and Methods - In a retrospective analysis, all patients with UOS admitted to our Stroke Unit from January to December 2018 were evaluated and classified as either WUS or DUS. - Results - 180 patients were included (74.4 % WUS, 25.6 % DUS). Compared to WUS patients, DUS patients received more often a non-contrast computed tomography initially (43.5 % vs. 24.6 %, p = 0.016). MR imaging was performed more frequently in WUS patients (53.7 % vs. 34.8 %, p = 0.027). The rate of mismatch findings in patients examined with either multimodal CT or MRI (126 patients, 101 WUS and 26 DUS) did not differ between the groups. Likewise, the rate of intravenous thrombolysis or mechanical thrombectomy was similar in both groups. DUS patients had more often severe neurological deficits at admission as defined by the National Institutes of Stroke Scale score (14.2 vs. 8.6, p < 0.001). - Conclusions - Patients with DUS had disadvantages in mismatch-based treatment options due to initial imaging modalities. Current data do not support different treatment concepts in WUS and DUS patients. All UOS patients should initially be evaluated by either multimodal CT or MRI to open a chance to receive reperfusion therapy. | ||
| 650 | 4 | |a Daytime-unwitnessed stroke | |
| 650 | 4 | |a Mismatch, Thrombolysis | |
| 650 | 4 | |a Unknown onset stroke | |
| 650 | 4 | |a Wake-up stroke | |
| 700 | 1 | |a Ebert, Anne |d 1971- |e VerfasserIn |0 (DE-588)122028635 |0 (DE-627)081691998 |0 (DE-576)175098344 |4 aut | |
| 700 | 1 | |a Szabo, Kristina |d 1970- |e VerfasserIn |0 (DE-588)120354993 |0 (DE-627)696594749 |0 (DE-576)292174942 |4 aut | |
| 700 | 1 | |a Förster, Alex |d 1978- |e VerfasserIn |0 (DE-588)132396971 |0 (DE-627)521958644 |0 (DE-576)299120112 |4 aut | |
| 700 | 1 | |a Alonso, Angelika |d 1977- |e VerfasserIn |0 (DE-588)1025166795 |0 (DE-627)721355315 |0 (DE-576)370025865 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of stroke and cerebrovascular diseases |d New York, NY : Elsevier, 1991 |g 30(2021), 7 vom: Juli, Artikel-ID 105842, Seite 1-6 |h Online-Ressource |w (DE-627)332166503 |w (DE-600)2052957-0 |w (DE-576)271585501 |x 1532-8511 |7 nnas |a Unknown onset stroke differences between patients with wake-up stroke and daytime-unwitnessed stroke |
| 773 | 1 | 8 | |g volume:30 |g year:2021 |g number:7 |g month:07 |g elocationid:105842 |g pages:1-6 |g extent:6 |a Unknown onset stroke differences between patients with wake-up stroke and daytime-unwitnessed stroke |
| 856 | 4 | 0 | |u https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.105842 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.sciencedirect.com/science/article/pii/S1052305721002457 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20220523 | ||
| 993 | |a Article | ||
| 994 | |a 2021 | ||
| 998 | |g 1025166795 |a Alonso, Angelika |m 1025166795:Alonso, Angelika |d 60000 |d 62700 |e 60000PA1025166795 |e 62700PA1025166795 |k 0/60000/ |k 1/60000/62700/ |p 5 |y j | ||
| 998 | |g 132396971 |a Förster, Alex |m 132396971:Förster, Alex |d 60000 |d 62700 |e 60000PF132396971 |e 62700PF132396971 |k 0/60000/ |k 1/60000/62700/ |p 4 | ||
| 998 | |g 120354993 |a Szabo, Kristina |m 120354993:Szabo, Kristina |d 60000 |e 60000PS120354993 |k 0/60000/ |p 3 | ||
| 998 | |g 122028635 |a Ebert, Anne |m 122028635:Ebert, Anne |d 60000 |d 62700 |e 60000PE122028635 |e 62700PE122028635 |k 0/60000/ |k 1/60000/62700/ |p 2 | ||
| 998 | |g 1258185857 |a Vedder, Katharina |m 1258185857:Vedder, Katharina |d 60000 |e 60000PV1258185857 |k 0/60000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1804096741 |e 4138102000 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"family":"Vedder","given":"Katharina","roleDisplay":"VerfasserIn","display":"Vedder, Katharina","role":"aut"},{"given":"Anne","roleDisplay":"VerfasserIn","family":"Ebert","role":"aut","display":"Ebert, Anne"},{"family":"Szabo","roleDisplay":"VerfasserIn","given":"Kristina","display":"Szabo, Kristina","role":"aut"},{"given":"Alex","roleDisplay":"VerfasserIn","family":"Förster","role":"aut","display":"Förster, Alex"},{"roleDisplay":"VerfasserIn","given":"Angelika","family":"Alonso","role":"aut","display":"Alonso, Angelika"}],"physDesc":[{"extent":"6 S."}],"title":[{"subtitle":"differences between patients with wake-up stroke and daytime-unwitnessed stroke","title":"Unknown onset stroke","title_sort":"Unknown onset stroke"}],"language":["eng"],"id":{"eki":["1804096741"],"doi":["10.1016/j.jstrokecerebrovasdis.2021.105842"]},"note":["Gesehen am 23.05.2022"],"name":{"displayForm":["Katharina Vedder, Dr. Anne Ebert, Prof. Dr. Kristina Szabo, Prof. Dr. Alex Förster, and Prof. Dr. Angelika Alonso"]},"relHost":[{"origin":[{"publisher":"Elsevier ; Saunders","dateIssuedDisp":"1991-","publisherPlace":"New York, NY ; Philadelphia, Pa.","dateIssuedKey":"1991"}],"type":{"bibl":"periodical","media":"Online-Ressource"},"recId":"332166503","disp":"Unknown onset stroke differences between patients with wake-up stroke and daytime-unwitnessed strokeJournal of stroke and cerebrovascular diseases","id":{"issn":["1532-8511"],"eki":["332166503"],"zdb":["2052957-0"]},"language":["eng"],"pubHistory":["1.1991 -"],"note":["Gesehen am 20.03.25"],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Journal of stroke and cerebrovascular diseases","subtitle":"official journal of the National Stroke Association and the Japan Stroke Society","title":"Journal of stroke and cerebrovascular diseases"}],"part":{"issue":"7","volume":"30","text":"30(2021), 7 vom: Juli, Artikel-ID 105842, Seite 1-6","year":"2021","extent":"6","pages":"1-6"}}],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1804096741","origin":[{"dateIssuedKey":"2021","dateIssuedDisp":"July 2021"}]} | ||
| SRT | |a VEDDERKATHUNKNOWNONS2021 | ||