Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect

There is increasing evidence that a defect of the gastrointestinal mucosal barrier is important for the development of inflammatory bowel diseases (IBD). The hydrophobicity of the colonic mucosal surface is a measure of its resistance to luminal antigens, e.g. of bacterial origin. Therefore, the pur...

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Bibliographic Details
Main Authors:	Gauss, Annika (Author) , Schönfeld, Ulrike (Author) , Welsch, Thilo (Author) , Kadmon, Martina (Author) , Funke, Benjamin (Author) , Gotthardt, Daniel (Author) , Zahn, Alexandra (Author) , Autschbach, Frank (Author) , Kienle, Peter (Author) , Zharnikov, Michael (Author) , Grunze, Michael (Author) , Stremmel, Wolfgang (Author) , Ehehalt, Robert (Author)
Format:	Article (Journal)
Language:	English
Published:	01 April 2011
In:	International journal of colorectal disease Year: 2011, Volume: 26, Issue: 8, Pages: 989-998
ISSN:	1432-1262
DOI:	10.1007/s00384-011-1190-z
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00384-011-1190-z
Author Notes:	Annika Braun, Ulrike Schönfeld, Thilo Welsch, Martina Kadmon, Benjamin Funke, Daniel Gotthardt, Alexandra Zahn, Frank Autschbach, Peter Kienle, Michael Zharnikov, Michael Grunze, Wolfgang Stremmel, Robert Ehehalt

MARC


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520			\|a There is increasing evidence that a defect of the gastrointestinal mucosal barrier is important for the development of inflammatory bowel diseases (IBD). The hydrophobicity of the colonic mucosal surface is a measure of its resistance to luminal antigens, e.g. of bacterial origin. Therefore, the purpose of this study was to determine this parameter in patients suffering from IBD.
650		4	\|a Crohn’s disease
650		4	\|a Hydrophobicity
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650		4	\|a Phosphatidylcholine
650		4	\|a Ulcerative colitis
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Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect

MARC

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