Reduced hydrophobicity of the colonic mucosal surface in ulcerative colitis as a hint at a physicochemical barrier defect

There is increasing evidence that a defect of the gastrointestinal mucosal barrier is important for the development of inflammatory bowel diseases (IBD). The hydrophobicity of the colonic mucosal surface is a measure of its resistance to luminal antigens, e.g. of bacterial origin. Therefore, the pur...

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Hauptverfasser: Gauss, Annika (VerfasserIn) , Schönfeld, Ulrike (VerfasserIn) , Welsch, Thilo (VerfasserIn) , Kadmon, Martina (VerfasserIn) , Funke, Benjamin (VerfasserIn) , Gotthardt, Daniel (VerfasserIn) , Zahn, Alexandra (VerfasserIn) , Autschbach, Frank (VerfasserIn) , Kienle, Peter (VerfasserIn) , Zharnikov, Michael (VerfasserIn) , Grunze, Michael (VerfasserIn) , Stremmel, Wolfgang (VerfasserIn) , Ehehalt, Robert (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 01 April 2011
In: International journal of colorectal disease
Year: 2011, Jahrgang: 26, Heft: 8, Pages: 989-998
ISSN:1432-1262
DOI:10.1007/s00384-011-1190-z
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s00384-011-1190-z
Volltext
Verfasserangaben:Annika Braun, Ulrike Schönfeld, Thilo Welsch, Martina Kadmon, Benjamin Funke, Daniel Gotthardt, Alexandra Zahn, Frank Autschbach, Peter Kienle, Michael Zharnikov, Michael Grunze, Wolfgang Stremmel, Robert Ehehalt
Beschreibung
Zusammenfassung:There is increasing evidence that a defect of the gastrointestinal mucosal barrier is important for the development of inflammatory bowel diseases (IBD). The hydrophobicity of the colonic mucosal surface is a measure of its resistance to luminal antigens, e.g. of bacterial origin. Therefore, the purpose of this study was to determine this parameter in patients suffering from IBD.
Beschreibung:Gesehen am 03.06.2022
Beschreibung:Online Resource
ISSN:1432-1262
DOI:10.1007/s00384-011-1190-z